N Hardcastle, NM Boulis, T Federici - Expert opinion on biological …, 2018 - Taylor & Francis
… Phase 1 clinical trials using AAVgene therapy for pediatric disorders – … of AAVgenedelivery to the spinal cord, particularly focusing on the most prominent AAVserotypes and delivery …
J Wang, SM Faust, JE Rabinowitz - Journal of molecular and cellular …, 2011 - Elsevier
… Over one hundred AAVserotypes have been described with … structures of multiple AAV serotypes have been solved (AAV2… AAVserotypes to the top of a list of promising genedelivery …
DS Yoon, KM Lee, S Cho, EA Ko, J Kim… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
… belonging to different serotypes. Potential differences between AAVserotypes may exist in … We aimed to determine the most efficient AAVserotype for the gene therapy of intra-articular …
… Direct injection of DRG for genedelivery may be preferable for some … AAVserotypes using this delivery method are not known. We have compared AAV vectors based on serotypes 1, 2, …
… of AAV in the ENS. The purpose of the current study was to examine the ability of various AAVserotypes to infect cells of the ENS. Adult rats received direct injections of AAV expressing …
PA Lawlor, RJ Bland, A Mouravlev, D Young… - Molecular therapy, 2009 - cell.com
… agent for somatic gene transfer into the central nervous system (CNS). To date, AAV-mediated genedelivery to the CNS is based on serotypes 1–9, with efficient gene transfer to …
L Tenenbaum, A Chtarto, E Lehtonen… - The Journal of Gene …, 2004 - Wiley Online Library
… Alternative AAVserotypes having different requirements than AAV2 are likely to show different cellular tropisms. For example, AAV5 using PDGFR is likely to harbor a different cellular …
RH Kofoed, CL Dibia, K Noseworthy, K Xhima… - Journal of Controlled …, 2022 - Elsevier
… As demonstrated in the current study, natural AAVserotypes provide genedelivery within the FUS spots in the brain with areas of transduction ranging from 0.01 mm 2 (AAV5, …
… AAV vectors. The current review is focused on naturally occurring AAVserotypes and engineering hybrid AAV … classification, and genedelivery applications of AAVserotypes have been …