… have become the primary delivery agent for somatic gene transfer into the … gene
delivery to the CNS is based on serotypes 1–9, with efficient gene transfer to neurons only—selective …

… We will review the different strategies that led to the recent development of efficient viral
vectors that can be successfully used to selectively transduce astrocytes in the mammalian brain…

… can mediate the transduction of resting lymphocytes by LV particles. Moreover, when
engineered for receptor targeting they can selectively transduce lymphocyte subtypes (Table I). …

… These AAV2 mosaic capsid vectors were able to selectively and efficiently transduce …
transduction of endothelial cells and could be efficiently purified without reduction in transduction …

… Many types of cells can be transduced depending on the route of administration. Direct
injection … The ability of the wild-type AAV to selectively integrate into chromosome 19 made it an …

… target for the evaluation of gene therapeutics. Of special … gene delivery for implementation
of a variety of cancer gene therapy approaches that are based on in vivo tumor transduction…

… gene delivery applications will expand the repertoire of gene … nonviral biological delivery
vehicles as gene therapy agents … to act as clinical gene therapy delivery vehicles has already …

… The αvβ3-NP selectively transduced GFP into M21 cells but not … gene delivery to either cell
type. A 20-fold molar excess of the soluble αvβ3 ligand completely abolished gene delivery to …

… a gene delivery vehicle, including its ability to grow as high-titer recombinant virus, large
transgene capacity, and efficient transduction … cleavage and selective retroviral transduction of …

… trials, due to higher gene delivery efficiency than nonviral … major concerns for their usage in
gene therapy. An adeno-associated … Selectively controlled, ordered, and targeted delivery of …