[HTML][HTML] themed issue: understanding the technical and social landscape of gene editing

R Dimond, J Lewis, G Thomas - New Genetics and Society, 2021 - Taylor & Francis
… in this themed issue is the relevance of gene editing for human health. Somatic gene editing
… Reproductive (germline) gene editing is more controversial, and there has been increasing …

Gene editing technologies and applications for insects

VM Gantz, OS Akbari - Current opinion in insect science, 2018 - Elsevier
… The increasingly refined ability to introduce altered traits into insects via genome editing
offers scientists exciting opportunities for tackling public health and environmental issues in …

Public acceptability of gene therapy and gene editing for human use: a systematic review

J Delhove, I Osenk, I Prichard, M Donnelley - Human gene therapy, 2020 - liebertpub.com
… There are also several ethical and philosophical issues related to gene therapy and gene
editing. Both can be targeted to the somatic cells, any cell other than the reproductive cells, or …

Genetics experience impacts attitudes towards germline gene editing: a survey of over 1500 members of the public

A Jedwab, DF Vears, C Tse, C Gyngell - Journal of Human Genetics, 2020 - nature.com
… our approach to genetic disease. However, the potential for genetic modification of embryos
… for ongoing stakeholder consultation about Germline Gene Editing (GGE), in particular lay …

Gene editing and CRISPR in the clinic: current and future perspectives

MP Hirakawa, R Krishnakumar, JA Timlin… - Bioscience …, 2020 - portlandpress.com
… In this review, we discuss the current state of gene editing technologies and their use as …
use of gene editors which include off-target effects, delivery issues, and immunogenicity of …

Encouraging science communication through deliberative pedagogy: A study of a gene editing deliberation in a nonmajors biology course

SA Mehltretter Drury, AG Bost… - … of Microbiology & …, 2018 - Am Soc Microbiol
… -scientific issues (SSI). This article examines a two-day deliberation module on gene editing
… connections between biology and real-world issues, thus contributing to the development of …

The Gene-Editing Conversation: Public dialogue about the new technology will require major investments from scientists, journalists, and philanthropists

M Nisbet - American Scientist, 2018 - go.gale.com
issues such as gene editing. These news organizations provide the information, frames
of reference, and narratives that scientists, journalists, funders, policy makers, and societal …

Advances in targeted genome editing

P Perez-Pinera, DG Ousterout, CA Gersbach - Current opinion in chemical …, 2012 - Elsevier
… Progress in genome editing has been the subject of several … the most significant advances
in genome editing in the last few … necessary to establish a genome editing technology that is …

CRISPR/Cas9 gene editing for genodermatoses: progress and perspectives

G Naso, A Petrova - Emerging Topics in Life Sciences, 2019 - portlandpress.com
… Furthermore, for pigmentation diseases, one of the key issues is to be able to regulate
gene expression in a spatial–temporal manner [67]. Finally, constraints related to the effective …

Ethical issues in genetic modification and why application matters

M Munsie, C Gyngell - Current Opinion in Genetics & Development, 2018 - Elsevier
… how research involving germline genome editing (a practice … for an international ban on any
gene editing research in human … for broad public discussion on the issue [15]. In December …