… In this study, we observed that a few genes were regulated during spheroid formation …
genes that turn on the mechanism as well as the link between calcium regulation and the genes …

… Interestingly, strong upregulation of these mediators in MSC spheroids is observed when
MSC spheroids are cultured in the regular cell culture medium (ie, alpha MEM supplemented …

… of MSC in spheroids compared to cells cultured in 2D conditions. By summarizing the data
for 3D MSC spheroids … advantages and perspectives of MSC spheroids use in regenerative …

… Second, the present study only analyzed the overall gene expression of MSC spheroids,
which contained heterogeneous populations of cells exposed to various niches and should …

… The aim of this study was to investigate the characteristics of MSC spheroids generated by
a 3D shaking culture method modified using neurosphere culture conditions to examine their …

… especially for the BDNF-transfected MSC spheroids. The transplanted MSCs were incorporated
… -mediated gene delivery and NP labeling may provide extra values for MSC spheroids to …

… in MSC spheroids using RNA-seq and that spheroid size may impact trophic factor
expression. Our results will be useful for future studies assessing the utility of MSC spheroids for …

… To further evaluate the proliferation potential of cells derived from the spheroids, MTT assay
was performed. Human MSC spheroids were dissociated with trypsin and seeded in culture …

… Enhanced proangiogenic properties of MSC spheroids have been confirmed in … of MSC
spheroid-containing tissue engineered structures. Murphy et al. [14] reported that MSC spheroids …

… In this study, MSC spheroids were transfected with plasmid DNA encoding runt-related
transcription factor 2 (Runx2) and tested for their ability to enhance bone regeneration. In vitro …