Genetic susceptibility to cancer: the role of polymorphisms in candidate genes

LM Dong, JD Potter, E White, CM Ulrich, LR Cardon… - Jama, 2008 - jamanetwork.com
gene association studies to current understanding of the genetic susceptibility to cancer. …
In this review of candidate gene association studies, nearly one-third of gene-variant cancer …

Genetic susceptibility to cervical cancer: role of common polymorphisms in apoptosis-related genes

SC Tan, R Ankathil - Tumor Biology, 2015 - Springer
polymorphisms in apoptosis-related genes play an important role in the genetic susceptibility
… the recent literatures on the role of common polymorphisms in apoptosis-related genes in …

Genetic polymorphisms and associated susceptibility to asthma

ME March, PMA Sleiman… - International journal of …, 2013 - Taylor & Francis
… -gene association studies. Additionally, single nucleotide polymorphisms (SNPs) in many
of these genesGenes important for T H 1 versus T H 2 T cell polarization, such as GATA3, …

[HTML][HTML] Polymorphisms

W Sukhumsirichart - Genetic diversity and disease susceptibility, 2018 - intechopen.com
… of skin or eyes, susceptible to diseases, … common polymorphism is single nucleotide
polymorphism (SNP) which is a single base change in a DNA sequence that occurs most commonly

Polymorphisms in the interleukin‐4 and interleukin‐4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population

B Beghé, S Barton, S Rorke, Q Peng… - Clinical & …, 2003 - Wiley Online Library
… (SNPs) have been identified in the coding region of the IL4RA gene, some of them leading
… of four common polymorphisms in the IL4 and IL4RA genes in conferring susceptibility to the …

[HTML][HTML] Role of genetic polymorphisms and ovarian cancer susceptibility

PA Fasching, S Gayther, L Pearce, JM Schildkraut… - Molecular …, 2009 - Elsevier
common polymorphisms in the CYP19A1 gene have been examined, driven by the hypothesis,
that these polymorphisms alter the function of the aromatase gene … these polymorphisms

Genetic polymorphisms and lung cancer susceptibility: a review

C Kiyohara, A Otsu, T Shirakawa, S Fukuda, JM Hopkin - Lung cancer, 2002 - Elsevier
susceptibilities of individuals. This review summarize data addressing the relationships of
lung … to markers of genetic susceptibility genes, including metabolic polymorphisms other than …

[HTML][HTML] Single nucleotide polymorphisms and cancer susceptibility

NA Deng, H Zhou, H Fan, Y Yuan - Oncotarget, 2017 - ncbi.nlm.nih.gov
… SNPs in genes that regulate DNA mismatch … with genetic susceptibility to cancer [1–12].
Understanding the mechanisms underlying the effects of SNPs that result in cancer susceptibility

Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer

TR Smith, MS Miller, K Lohman, EM Lange, LD Case… - Cancer letters, 2003 - Elsevier
… variants of DNA repair genes could alter either DNA repair capacity or fidelity, which may
contribute to cancer susceptibility. We selected three polymorphisms of two genes for this study…

[HTML][HTML] Common and rare variants in multifactorial susceptibility to common diseases

W Bodmer, C Bonilla - Nature genetics, 2008 - nature.com
… frequency variation that may be much more likely to become the basis for some sort of
personalized medicine, than that usually discussed in relation to common polymorphic variation. …