Genetic analysis reveals role of testosterone levels in human disease.

C Greenhill - Nature Reviews Endocrinology, 2020 - go.gale.com
… We have shown that testosterone levels in men and … genetic variants and genes "It is
important to state that we do not recommend anyone to take medication to alter testosterone levels

Genetic analyses implicate complex links between adult testosterone levels and health and disease

JT Leinonen, N Mars, LE Lehtonen… - Communications …, 2023 - nature.com
… Variable testosterone levels explain some differences in human … study how adult testosterone
levels relate to health and disease. Genetic, ie inherited, differences in testosterone levels

Genetic determinants of serum testosterone concentrations in men

…, M Maggio, AD Coviello, EMAS Study Group… - … genetics, 2011 - journals.plos.org
… of serum testosterone. Here we perform a large-scale genome-wide association study to
examine the effects of common genetic variants on serum testosterone concentrations. By …

Using human genetics to understand the disease impacts of testosterone in men and women

KS Ruth, FR Day, J Tyrrell, DJ Thompson, AR Wood… - Nature medicine, 2020 - nature.com
study participants. Using 2,571 genome-wide significant associations, we demonstrate that
the genetic determinants of testosterone levels … importance of sex-specific genetic analyses. …

Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men

N Pitteloud, VK Mootha, AA Dwyer, M Hardin… - Diabetes …, 2005 - Am Diabetes Assoc
… Recent studies using genetic analysis (1,2), functional imaging (3,4), and … In this study, we
demonstrate that testosterone levels correlate positively with Vo 2max and OXPHOS-CR gene

Environmental and genetic contributors to salivary testosterone levels in infants

K Xia, Y Yu, M Ahn, H Zhu, F Zou, JH Gilmore… - Frontiers in …, 2014 - frontiersin.org
analysis, univariate genetic analyses, and RF analysis, we also performed sensitivity analyses
in infants with transferrin levels <… study impacted salivary testosterone levels in females. …

Genetic and environmental contributions to saliva testosterone levels in male and female infant twins

D Caramaschi, L Booij, A Petitclerc, M Boivin… - …, 2012 - Elsevier
study aimed at disentangling the genetic and environmental contributions to testosterone
levels … data were excluded from the genetic analysis, bringing the final sample for the genetic

Large-Scale Analysis of the Relationship between CYP11A Promoter Variation, Polycystic Ovarian Syndrome, and Serum Testosterone

M Gaasenbeek, BL Powell, U Sovio… - The Journal of …, 2004 - academic.oup.com
… undergone clinical review and DNA sampling at age 31, we genotyped 1589 for this study
(22). … , fasting samples were used for the analysis of testosterone levels. For the UK subjects, …

Genetic and environmental influences of daily and intra-individual variation in testosterone levels in middle-aged men

MS Panizzon, R Hauger, KC Jacobson… - …, 2013 - Elsevier
… in testosterone level throughout the day are genetically influenced. The aim of the present
study was to determine the degree to which genetic … differences in testosterone throughout the …

Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men

MS Panizzon, RL Hauger, LJ Eaves, CH Chen… - Neuroimage, 2012 - Elsevier
genetic factors) would vary as a function of testosterone level. Put another way, we examined
whether the level of testosterone alters the balance of latent genetic … In the present study, …