Sex-specific differences in genetic and nongenetic determinants of mean platelet volume: results from the Gutenberg Health Study

M Panova-Noeva, A Schulz… - Blood, The Journal …, 2016 - ashpublications.org
platelet volume (MPV), a measure of platelet size, is a potential biological marker of platelet
… To date, a comprehensive analysis including known genetic and nongenetic factors that …

Variability of platelet indices and function: acquired and genetic factors

G de Gaetano, I Santimone, F Gianfagna, L Iacoviello… - Antiplatelet …, 2012 - Springer
… linked to genetic or acquired abnormal platelet number or platelet dysfunction. In contrast,
it is less obvious that the variability of platelet phenotypes (number, mean platelet volume, …

Genetics of platelet traits in ischaemic stroke: focus on mean platelet volume and platelet count

K Vasudeva, A Munshi - International Journal of Neuroscience, 2019 - Taylor & Francis
… groups and will recognise the role of genetic factors rendering differences to MPV and PLT
on … fluctuations) and genetic factors in determining the variability in MPV and PLT in terms of …

A population-based study of an Italian genetic isolate reveals that mean platelet volume is not a risk factor for thrombosis

G Biino, L Portas, F Murgia, S Vaccargiu… - Thrombosis research, 2012 - Elsevier
… In conclusion, our epidemiologic study in the general population of a genetic isolate confirmed
several well known risk factors for thrombosis, but failed to identify any predictive capacity …

Mean Platelet Volume and Arterial Stiffness–Clinical Relationship and Common Genetic Variability

M Panova-Noeva, N Arnold, MI Hermanns… - Scientific Reports, 2017 - nature.com
… variable and adjustment for age, cardiovascular risk factors (CVRFs), comorbidities and
medication was used to identify determinants of arterial stiffness. The analysis of prospective …

Genetic variation of platelet function and pharmacology: an update of current knowledge

T Geisler, E Schaeffeler, M Gawaz… - Thrombosis and …, 2013 - thieme-connect.com
… of platelet reactivity, platelet volume and count and function of … to genetic variation, other
clinical, disease-related and demographic factors are important so-called non-genetic factors. …

Mean platelet volume and its genetic variants relate to stroke severity and 1-year mortality

MM Miller, N Henninger, A Słowik - Neurology, 2020 - AAN Enterprises
… The mean platelet volume (MPV) is a readily available parameter that indirectly reflects
platelet activity. … parameters, such as the MPV, are in part determined by genetic factors. …

Genetic and non-genetic factors affecting the response to clopidogrel therapy

M Karaźniewicz-Łada, D Danielak… - Expert opinion on …, 2012 - Taylor & Francis
… is multifactorial and includes genetic polymorphisms and non-genetic causes (such as drug…
the role of genetic polymorphisms and non-genetic factors, as determinants of the antiplatelet …

Quantile-specific heritability of mean platelet volume, leukocyte count, and other blood cell phenotypes

PT Williams - Lifestyle Genomics, 2022 - karger.com
… the effect size of a genetic variant depends upon whether the phenotype (eg, mean platelet
volume, … Sex-specific differences in genetic and nongenetic determinants of mean platelet

Genetic and nongenetic drivers of platelet reactivity in healthy Tanzanian individuals

VI Kullaya, GS Temba, N Vadaq, J Njau… - Journal of Thrombosis …, 2024 - Elsevier
… We aimed to investigate the nongenetic and genetic determinants of platelet reactivity in …
of platelet parameters with host genetic and nongenetic factors, environmental factors, plasma …