[HTML][HTML] Genetic architecture of host proteins involved in SARS-CoV-2 infection

M Pietzner, E Wheeler, J Carrasco-Zanini… - Nature …, 2020 - nature.com
… the genetic architecture of 179 host proteins relevant to COVID-19. We identify genetic
variants that regulate host proteins … to the maladaptive host response. We deeply characterize …

[HTML][HTML] Genetic architecture of host proteins interacting with SARS-CoV-2

M Pietzner, E Wheeler, J Carrasco-Zanini, J Raffler… - BioRxiv, 2020 - ncbi.nlm.nih.gov
… the genetic architecture of 179 host proteins relevant to COVID-19. We identified genetic
variants that regulate host proteins … to the maladaptive host response. We deeply characterized …

Host genetic architecture in single and multiple infections

KM Wegner, C Berenos… - Journal of evolutionary …, 2009 - academic.oup.com
… Potential differences in what kind of genetic architecturegenetic architecture underlying
resistance either in single or multiple infections. In particular, we studied the genetic architecture

[HTML][HTML] Combining multiple approaches and models to dissect the genetic architecture of resistance to infections in fish

C Fraslin, E Quillet, T Rochat, N Dechamp… - … in genetics, 2020 - frontiersin.org
… Such genes can significantly affect host susceptibility to a pathogen. However, host
resistance or susceptibility is determined by a much wider repertoire of genes: any host protein

Beyond the phenotypic gambit: molecular behavioural ecology and the evolution of genetic architecture

SA Springer, BJ Crespi, WJ Swanson - Molecular Ecology, 2011 - Wiley Online Library
… the evolution of genetic architectures. Our aim is not to describe the genetics of behaviour in
… splicing of a protein-coding region or gene duplication would be favoured when the same …

[HTML][HTML] Enteric neuromics: how high-throughput “omics” deepens our understanding of enteric nervous system genetic architecture

C Dharshika, BD Gulbransen - Cellular and Molecular Gastroenterology …, 2023 - Elsevier
gene and/or protein expression of functional neuronal and glial cell subtypes and suggest
expression patterns of novel subtypes. Gene and protein … unique gene and protein expression …

Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection

LB Barreiro, L Tailleux, AA Pai… - Proceedings of the …, 2012 - National Acad Sciences
… Using the protein secretion data we also looked for protein QTL (pQTL), namely loci that are
… 200 kb of the TSSs of the genes encoding the measured proteins. However, when we only …

[HTML][HTML] Type VI secretion systems of human gut Bacteroidales segregate into three genetic architectures, two of which are contained on mobile genetic elements

MJ Coyne, KG Roelofs, LE Comstock - BMC genomics, 2016 - Springer
… for the transfer of genetic architecture 1 T6SS loci among co-… fifth protein encoded by all
three T6SS genetic architectures of … proteins, searches of all 205 genomes showed that genes

Genome‐wide association and epistasis studies unravel the genetic architecture of sudden death syndrome resistance in soybean

J Zhang, A Singh, DS Mueller, AK Singh - The Plant Journal, 2015 - Wiley Online Library
… Finally, the products of chitin-responsive genes and pathogenesis-related proteins are … of
the host plant. However, further research is required to validate the predicted causal genes and …

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations

G Thareja, A Belkadi, M Arnold… - … molecular genetics, 2023 - academic.oup.com
… disease, with numerous blood circulating protein levels representing functional readouts
of … the genetic architecture of a comprehensive set of blood-circulating proteins between a …