Genetic association studies

HJ Cordell, DG Clayton - The Lancet, 2005 - thelancet.com
… However, genetic associations arise only because human populations share common
ancestry and it has been argued that association studies are really just a special form of linkage …

A comprehensive review of genetic association studies

JN Hirschhorn, K Lohmueller, E Byrne… - Genetics in …, 2002 - nature.com
… in MTHFR, the gene encoding methylene tetrahydrofolate reductase. … association studies,
because proper evaluation of these associations is critical both to understanding the genetics

Introduction to genetic association studies

CM Lewis, J Knight - Cold Spring Harbor Protocols, 2012 - cshprotocols.cshlp.org
genetic association studies, but it focuses specifically on case–control studies in candidate
genes … Even in this era of genome-wide studies, case–control studies still form the majority of …

Meta-analysis of genetic association studies

MR Munafo, J Flint - TRENDS in Genetics, 2004 - cell.com
… for resolving discrepancies in genetic association studies. Persistent difficulties in … in genetic
association studies are almost certainly because genetic effects are small, requiring studies

Bayesian statistical methods for genetic association studies

M Stephens, DJ Balding - Nature Reviews Genetics, 2009 - nature.com
… to the assessment of association between genetic variants and … tests in genome-wide
association studies. We discuss the … robust conclusions from future genetic association studies. …

Genetic association studies

KL Lunetta - Circulation, 2008 - Am Heart Assoc
genetic polymorphisms at once, genetic association studiesgenetic association studies;
it then discusses the primary features differentiating genetic from standard association studies

Efficiency and power in genetic association studies

PIW De Bakker, R Yelensky, I Pe'er, SB Gabriel… - … genetics, 2005 - nature.com
We investigated selection and analysis of tag SNPs for genome-wide association studies by
specifically examining the relationship between investment in genotyping and statistical …

[HTML][HTML] Meta-analysis of genetic association studies

YH Lee - Annals of laboratory medicine, 2015 - ncbi.nlm.nih.gov
… of genetic association studies is … Genetic association studies of candidate genes have shown
that the majority of initial positive associations cannot be reproduced in subsequent studies

Replication validity of genetic association studies

J Ioannidis, EE Ntzani, TA Trikalinos… - … genetics, 2001 - nature.com
… by meta-analysis 370 studies addressing 36 genetic associations for various … genetic
association studies require cautious replication—an issue for both linkage and association studies

Interpretation of genetic association studies in complex disease

H Campbell, I Rudan - The pharmacogenomics journal, 2002 - nature.com
The potential of the genetic association approach for the identification of genetic variants that
alter susceptibility to common complex disease is well recognised. 1 This potential equally …