Genetic associations with hypertension: meta-analyses of six candidate genetic variants

C Zhang, L Wang, Q Liao, L Zhang, L Xu… - Genetic testing and …, 2013 - liebertpub.com
… combined analyses of six genetic variants for the risk of hypertension. Methods: … genetic
variants involved with the association study of hypertension, we harvested a total of five genes (…

Association of hypertension drug target genes with blood pressure and hypertension in 86 588 individuals

AD Johnson, C Newton-Cheh, DI Chasman… - …, 2011 - Am Heart Assoc
… We identified a priori 30 candidate genes that code for proteins that are direct … genes. We
analyzed all of the CHARGE BP/hypertension associations within 60 kb of each target gene

Genetic basis of blood pressure and hypertension

S Padmanabhan, C Newton-Cheh, AF Dominiczak - Trends in Genetics, 2012 - cell.com
… , identifying genes that contribute to BP and HTN has … genetic architecture of BP and HTN,
which has accelerated over the past five years primarily owing to genome-wide association

Genetic and molecular aspects of hypertension

S Padmanabhan, M Caulfield… - Circulation research, 2015 - Am Heart Assoc
genes have been associated with levels of the gene product and … of hypertensive and 26%
of normotensive subjects and is a major public health problem. Candidate gene association

Associations between hypertension and genes in the renin-angiotensin system

X Zhu, YPC Chang, D Yan, A Weder, R Cooper… - …, 2003 - Am Heart Assoc
… system genes contributes to hypertension risk. … Genes that encode components of the
RAS are in turn thought to play a role in determining genetic susceptibility to hypertension and …

Genetics of hypertension and cardiovascular disease and their interconnected pathways: lessons from large studies

AT Kraja, SC Hunt, DC Rao, VG Dávila-Román… - Current hypertension …, 2011 - Springer
… Can we conclude from these modest significant associations that RYR2 is an important gene
… that the identification of hypertension and CVD susceptible genes has a long road ahead. …

An exploration of genegene interactions and their effects on hypertension

Y Meng, S Groth, JR Quinn… - International journal of …, 2017 - Wiley Online Library
… -wide discovery analysis and a confirmatory association analysis. Furthermore, the contribution
of GxG … of hypertension-related genes [53], and gene-environmental interactions, such as …

Combinations of variations in multiple genes are associated with hypertension

SM Williams, JH Addy, JA Phillips III, M Dai… - …, 2000 - Am Heart Assoc
… of a single gene underlie the genetic basis of hypertension in our … The genetic basis of
essential hypertension is complex. … previous association studies on various candidate genes with …

Genetic variations related to hypertension: a review

MOM Tanira, KA Al Balushi - Journal of human hypertension, 2005 - nature.com
genes rather than a single gene account for the heritability of this complex disorder. However,
the genetic analysis of hypertensionassociation between specific genes and hypertension

Causal associations and shared genetics between hypertension and COVID‐19

A Baranova, H Cao, F Zhang - Journal of Medical Virology, 2023 - Wiley Online Library
… To identify overlapping risk genes between COVID-19 and hypertension, we compared
genomic loci of the two traits from their GWAS datasets. Functional mapping and annotation (…