… genetic mechanisms that specify early kidneydevelopment, the Xenopus tadpole and zebrafish larvae are excellent model systems for genetic … the same genes found in the developing …
MS Lechner, GR Dressler - Mechanisms of development, 1997 - Elsevier
… of kidneydevelopment. Current studies using combinations of these techniques – expression analyses, gene … of the various genes and gene products to their specific role in early kidney …
… A role for this molecule in kidneydevelopment was revealed in a gene-trapping experiment that inserted the lac-z gene into the Hs2st coding region (Bullock et al., 1998). Analysis of lac-…
S Vainio, Y Lin - Nature Reviews Genetics, 2002 - nature.com
… Gene-targeting experiments have greatly improved our understanding of kidneydevelopment, and have revealed many important genes that regulate early kidney organogenesis, …
I Pietilä, SJ Vainio - Nephron Experimental Nephrology, 2014 - karger.com
… , the basic cellular forces that are behind kidney ontogenesis are known. Gene-mapping studies have revealed a wealth of candidate genes that may be behind kidneydevelopment in …
WM Linehan, MM Walther, B Zbar - The Journal of urology, 2003 - auajournals.org
… We identified the geneticbasis of these different types of kidney … for the development of molecular therapeutic approaches. … for the development of a molecular genetic classification of …
MH Little, AP McMahon - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
… The geneticbasis of such ciliopathies is an area that has expanded enormously based on … of fetal kidneydevelopment and the normal response of the adult kidney to damage. No new …
… Although identification of individual genes required for normal kidneydevelopment is proceeding at a rapid rate with mouse transgenic technology, it should be emphasized that we are …
… , gene expression patterns, and gene copy number, will be required to gain a complete understanding of the geneticbasis of kidney cancer and of the kidney cancer gene pathways and…