Towards a genetic basis for kidney development

JBL Bard, JE McConnell, JA Davies - Mechanisms of development, 1994 - Elsevier
… several genetic disorders associated with its development, … of kidney development are
controlled at the genetic level. For … the more than forty regulatory genes thus far identified are …

The cellular basis of kidney development

GR Dressler - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
genetic mechanisms that specify early kidney development, the Xenopus tadpole and zebrafish
larvae are excellent model systems for genetic … the same genes found in the developing

[HTML][HTML] The molecular basis of embryonic kidney development

MS Lechner, GR Dressler - Mechanisms of development, 1997 - Elsevier
… of kidney development. Current studies using combinations of these techniques – expression
analyses, gene … of the various genes and gene products to their specific role in early kidney

Overview: the molecular basis of kidney development

TJ Carroll, AP McMahon - The kidney, 2003 - Elsevier
… A role for this molecule in kidney development was revealed in a gene-trapping experiment
that inserted the lac-z gene into the Hs2st coding region (Bullock et al., 1998). Analysis of lac-…

Coordinating early kidney development: lessons from gene targeting

S Vainio, Y Lin - Nature Reviews Genetics, 2002 - nature.com
Gene-targeting experiments have greatly improved our understanding of kidney development,
and have revealed many important genes that regulate early kidney organogenesis, …

Kidney development: an overview

I Pietilä, SJ Vainio - Nephron Experimental Nephrology, 2014 - karger.com
… , the basic cellular forces that are behind kidney ontogenesis are known. Gene-mapping
studies have revealed a wealth of candidate genes that may be behind kidney development in …

The genetic basis of cancer of the kidney

WM Linehan, MM Walther, B Zbar - The Journal of urology, 2003 - auajournals.org
… We identified the genetic basis of these different types of kidney … for the development of
molecular therapeutic approaches. … for the development of a molecular genetic classification of …

Mammalian kidney development: principles, progress, and projections

MH Little, AP McMahon - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
… The genetic basis of such ciliopathies is an area that has expanded enormously based on
… of fetal kidney development and the normal response of the adult kidney to damage. No new …

Regulatory molecules in kidney development

CR Burrow - Pediatric nephrology, 2000 - Springer
… Although identification of individual genes required for normal kidney development is
proceeding at a rapid rate with mouse transgenic technology, it should be emphasized that we are …

Genetic basis of kidney cancer: role of genomics for the development of disease-based therapeutics

WM Linehan - Genome research, 2012 - genome.cshlp.org
… , gene expression patterns, and gene copy number, will be required to gain a complete
understanding of the genetic basis of kidney cancer and of the kidney cancer gene pathways and…