Defining the genetic blueprint of kidney development

SS Potter, EW Brunskill, LT Patterson - Pediatric Nephrology, 2011 - Springer
gene expression strategies to study kidney development. … in kidney development, provide
new molecular markers to aid in the analysis of mutant phenotypes, lend insight into genetic

Defining Genetic BlueprintsKidney and Craniofacial Development

EW Brunskill, AS Potter, SS Potter - Pediatric Biomedical Informatics …, 2012 - Springer
… of the forming kidney when one could not be sure which genes were being … gene expression
patterns in order to generate a useful genomics level understanding of kidney development

[HTML][HTML] A transcriptional blueprint for human and murine diabetic kidney disease

V Bhalla, MG Velez, GM Chertow - Diabetes, 2013 - ncbi.nlm.nih.gov
… and kidney disease are … ), kidney disease in patients with diabetes is crudely defined. This
work may help to redefine the taxonomy of diabetic kidney disease based on glomerular gene

Genomics in nephrology: identifying informatics opportunities to improve diagnosis of genetic kidney disorders using a human-centered design approach

KM Romagnoli, ZM Salvati, DK Johnson… - Journal of the …, 2024 - academic.oup.com
… The service blueprints and workflow process maps developed in this work offer a novel,
complementary, and visual approach to communicating qualitative findings in a compelling, …

Normal and abnormal development of the kidney: a clinician's interpretation of current knowledge

KI Glassberg - The Journal of urology, 2002 - Elsevier
… with new discoveries in the molecular genetics of renal development. However, little of this
… and propose a more sophisticated blueprint of renal development than the one traditionally …

[PDF][PDF] Atlas of gene expression in the developing kidney at microanatomic resolution

EW Brunskill, BJ Aronow, K Georgas, B Rumballe… - Developmental cell, 2008 - cell.com
gene expression atlas of the developing mouse kidney based on … This kidney atlas allows a
comprehensive analysis of the … view of the gene expression blueprint of kidney development. …

The European Renal Genome Project: an integrated approach towards understanding the genetics of kidney development and disease

TE Willnow, C Antignac, AW Brändli… - …, 2005 - Taylor & Francis
… Deciphering the three billion base pairs of the mammalian genome provides us with a
blueprint of the genetic map that defines the activities of cells and tissues, organs and entire …

Genetic determination of nephrogenesis: the Pax/Eya/Six gene network

S Brodbeck, C Englert - Pediatric nephrology, 2004 - Springer
… The first sign of kidney development is the interaction … genes that play a crucial role in early
kidney development, such as Pax2, Eya1, Six1, Six2, Sall1, Foxc1, Wt1, and the Hox11 genes

Principles of human and mouse nephron development

J Schnell, MA Achieng, NO Lindström - Nature Reviews Nephrology, 2022 - nature.com
kidney diseases can arise. Studies of kidney development in vivo have also facilitated efforts
to … nephrogenesis in kidney organoids in vitro, by providing a detailed blueprint of signalling …

Temporal and spatial transcriptional programs in murine kidney development

G Challen, B Gardiner, G Caruana… - Physiological …, 2005 - journals.physiology.org
… the most thorough gene expression profile of kidney development to date. The activity of
some 18,000 genes has been assessed throughout all stages of kidney development and using …