… CRISPR-Cas9 is an RNA-mediated adaptive immune system that protects bacteria and …
the recent development of CRISPR-Cas9 into a key technology for genome editing, targeting, …

… Cas9 function and the structural and biochemical studies that support it. We focus on the
applications of Cas9 for genome editing… many advantages that CRISPR/Cas9 technology offers. …

… The specificity of CRISPR/Cas9-mediated DNA cleavage requires target sequences …
CRISPR/Cas9-mediated genome editing and clinical therapeutic potential of CRISPR/Cas9 …

… practical guide to interested users of genome editing technologies, highlighting key tools
and strategies for optimizing specificity. The genome editing community should now strive to …

… support the legalization of CRISPR/Cas9-based genome editing studies in human zygotes.
… demonstrated the possibility of CRISPR/Cas9-mediated genome editing in primary somatic …

… genome editing. Further, this review provides information on CRISPR tools used for genome
editing, … loci, strategies for delivering CRISPR–Cas9 to cells under study and applications of …

… of the CRISPR-Cas9 genome-editing … CRISPR-Cas9 system to edit gene sequences.
We will then highlight the current systems that have been developed to deliver the CRISPR-Cas9 …

… to fully realize the medical potential of CRISPR-Cas9. In this article, we … CRISPR-Cas9
technology and provide perspectives for the ultimate perfection of Cas9-mediated genome editing…

… the utilization of CRISPR/Cas9 in a variety of … of CRISPR/Cas9-mediated gene editing in
human cells, especially in embryos. Because ethical concerns preclude studies of gene editing …

… gene correction, gene replacement, and gene knock-in. In this review, we briefly survey
the history of the CRISPR/Cas9 system invention and its genome-editing … of the CRISPR/Cas9 …