… genomeeditinginterventions can be therapeutic in nature, and thus that it is false that all such interventions … are met by certain reproductive genomeeditinginterventions. I then defend …
R Ranisch - Bioethics, 2020 - Wiley Online Library
… of new tools for geneediting such as CRISPR/Cas9. Recently, germline genomeediting (GGE) … Since then, a handful of studies have reported experiments with geneediting techniques …
… is to produce a genomeediting tool with high editing specificity, high editing efficiency and minimal off-target creation of by-projects, which is not within the gene of interest.30 NHEJ, …
… Heritable genomeeditinginterventions should only be permitted provided that legitimate … of health economics arising from heritable genomeeditinginterventions for health services."" …
… sequencing and explain how the presence of these genome resources in combination with geneediting techniques has revolutionized the procedures of trait discovery and …
ET Juengst, GE Henderson, RL Walker… - The CRISPR …, 2018 - liebertpub.com
… The stated goal of this research is to develop somatic human geneediting interventions to prevent age-associated degenerative neurological conditions such as Alzheimer's disease by …
C Addison, S Taylor-Alexander - Molecular Therapy, 2015 - cell.com
… We contend that the response of the scientific community to the debate on geneediting could … They also present an opportunity for dialogue that can enhance the impact of geneediting …
… However, a challenge for the development of international guidelines is that the technical procedures and effects of clinical heritable genomeeditinginterventions are different for each …
R Ranisch, K Trettenbach, G Arnason - Medicine, Health Care and …, 2023 - Springer
… on research ethics issues in germline genomeediting by exploring key issues … genome editing into clinical practice, we outline the specific challenges associated with such interventions …