… psychiatric disorders, including alcohol dependence, nicotine dependence, and cannabis use
disorder. … We then used the genetic relationships to model a latent genetic factor structure. …

… the shared genetic basis of these eight disorders: (1) Can we identify a shared genetic
structure within the broad range of these clinically distinct psychiatric disorders? (2) Can we …

… to individual disorders or shared across disorders is unclear. … genome-wide genotype data
from the Psychiatric Genomics … bipolar disorder, major depressive disorder, autism spectrum …

… to individual disorders or shared across disorders is unclear. … genome-wide genotype data
from the Psychiatric Genomics … bipolar disorder, major depressive disorder, autism spectrum …

… architectures of different psychiatric disorders can strongly overlap, we are challenged to
re-evaluate and refine the diagnostic architectures of psychiatric disorders with respect to …

… Here, we review recent evidence from family and genomic studies, which support an
overlapping and complex genetic architecture for psychiatric disorders and provide new avenues …

… Similar success evades genetic analysis of other psychiatric disorders, for which we have
very few large-effect genes that have been independently replicated. Work on SCZ is closest to …

… apply genomic structural equation modeling (genomic SEM) … psychiatric disorders (average
total sample size per disorder = … functional genomic and molecular genetic levels of analysis. …

… psychiatric disorders are the results of our evolutionary past. The evolutionary forces that
shaped our modern genomes … Although there are multiple theories of what our genomes should …

… correlated psychiatric disorders, ANX and DEP (genome-wide … for either psychiatric disorder
in the psychiatric disorder pair, … multiple psychiatric disorders for three functional genomic …