High glycemic variability is associated with worse continuous glucose monitoring metrics in children and adolescents with type 1 diabetes

C Piona, M Marigliano, E Mozzillo… - Hormone Research in …, 2021 - karger.com
… and adolescents with worse glycemic control at higher risk of … metric for the evaluation of
glycemic variability of patients with … levels is ≤36%, while a CV >36% indicates high glycemic

A Genome-Wide Scan for Loci Linked to Plasma Levels of Glucose and HbA1c in a Community-Based Sample of Caucasian Pedigrees: The Framingham Offspring …

JB Meigs, CIM Panhuysen, RH Myers, PWF Wilson… - Diabetes, 2002 - Am Diabetes Assoc
… For each glycemic trait, we used SOLAR to partition the total genetic variance into … Maximum
multipoint LOD scores for glycemic traits by chromosome and associated Marshfield marker …

Associations between glycemic traits and colorectal cancer: a Mendelian randomization analysis

N Murphy, M Song, N Papadimitriou… - JNCI: Journal of the …, 2022 - academic.oup.com
… for each glycemic trait, we excluded correlated SNPs based on a linkage disequilibrium level
of R … The proportion of variance explained by the genetic instruments for the glycemic traits

Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study

MK Georgakis, EL Harshfield, R Malik, N Franceschini… - Neurology, 2021 - AAN Enterprises
… its levels via both erythrocyte and glycemic biology, we provided support for the latter, as
the effects were stronger when focusing on variants not associated with erythrocyte traits. …

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

V Lagou, R Mägi, JJ Hottenga, H Grallert… - Nature …, 2021 - nature.com
… These results position dissection of metabolic and glycemic health sex dimorphism as a
steppingstone for understanding differences in genetic effects between women and men in …

The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: a systematic review

T Muka, J Nano, T Voortman, KVE Braun… - Nutrition, Metabolism …, 2016 - Elsevier
… and glycemic traits including glucose levels, insulin levels and … with type 2 diabetes and
glycemic traits are summarized and … associated with 2 h post-oral glucose tolerance test levels. …

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

RA Scott, V Lagou, RP Welch, E Wheeler… - Nature …, 2012 - nature.com
… of confirmed loci influencing glycemic traits to 53, of which 33 also increase type 2 diabetes
risk (q < 0.05). Loci influencing fasting insulin concentration showed association with lipid …

Insulin resistance in type 1 diabetes mellitus and its association with patient's micro-and macrovascular complications, sex hormones, and other clinical data

D Šimonienė, A Platūkiene, E Prakapienė… - Diabetes Therapy, 2020 - Springer
… and eGDR level was observed (r = 0.33, p = 0.04), ie, men with higher testosterone level had
… Still, in later results from DCCT, intensive glycemic control was associated with better CVD …

Serum metabolomics of incident diabetes and glycemic changes in a population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos

JC Chai, GC Chen, B Yu, J Xing, J Li, T Khambaty… - Diabetes, 2022 - Am Diabetes Assoc
… metabolite module both had inverse correlations with glycemic traits, while other metabolite
modules were positively correlated with glycemic traits, especially fasting insulin and HOMA-…

Testosterone deficiency or male hypogonadism

CA Koch, M Zitzmann - Endocrine Hypertension: Underlying Mechanisms …, 2013 - Springer
… has beneficial metabolic effects with an improved glycemic … total testosterone level should
exceed 350 ng/dL to reliably predict normal free testosterone and that total testosterone levels