… publications on hepatic drug transporter DDIs using static models that tackle interactions
with individual transporters and in combination with other drug transporters and metabolising …

… method, imaging methodologies for studying drug (or solute) transport in vivo are rapidly
emerging 19– 21 . These approaches … drug transporters could also be new drug transporters. …

… The RAF method for transporters is similar to the approach utilized for estimating the
contribution of each CYP isoenzymes to the overall metabolism of an NCE Citation[64]. Uptake …

… hepatic drug transporters in clinical DDIs, pharmacogenetics, drug-induced liver injury (DILI),
as well as methods for predicting transporter-… -MS/MS based proteomic approaches for func…

… Existing challenges and approaches to examine the involvement of transporters in drug …
of disease state alterations in transporters (eg, altered hepatic transporters in underlying liver …

… The effect of these methods on hepatic drug-transporter … Conventional approaches to
counteract this dedifferentiation … Most of these methods clearly positively affect drug transporters. …

… , methods, and modeling/simulation approaches used to … (iii) experimental and modeling
approaches that may be used … of transporters and enzyme–transporter interplay on hepatic …

… RNA targeting specific intestinal transporters or other knockdown methods such as Sigma’s …
Hepatic transporters are increasingly recognized to play a significant role in the distribution …

… and modeling approaches for evaluating hepatic clearance and … modeling approaches
are key for understanding transporter–… Current methodologies incur limitations and emphasis …

… two data analysis methods with priority assigned to the targeted approach. A list of … methods
in measuring the effects of liver disease on expression of hepatic enzymes and transporters…