… -1β expression and inflammasome activation. We conclude that HIV-1 infection induced the
… mechanisms and activated caspase-1 through the NLRP3 inflammasome to cleave pro-IL-1β …

… role of the NLRP3 inflammasome in mediating caspase-1 … HIV-1 disease progression (Figure
5A). Moreover, we identified the NLRP3 inflammasome as a sensor that drives caspase-1 …

… Taken together, these studies indicate that the NLRP3 inflammasome can be activated
by HIV-1-derived RNA and viral proteins to mediate inflammatory responses and …

… role of HIV-1 infection in activation of the NLRP3 inflammasome and the role of NLRP3
activation … HIV-1 infection can mediate NLRP3 inflammasome activation, thus potentiating a pro-…

… in HIV-1-infected patients. Here we evaluate whether HIV-1 can induce activation of the NLRP3
inflammasome. … were infected with HIV-1 in the absence or presence of classical NLRP3 …

… Because HIV-1 Transactivator of Transcription (Tat) protein continues to be present despite
… prime the NLRP3 inflammasome. We found a dose- and time-dependent induction of NLRP3 …

… of HIV. The purpose of this review is to depict the double-faced inflammasome role in HIV-1 …
Moreover it has been observed that HIV-1 Tat protein up-regulates NLRP3 inflammasome …

… data revealed that the NLRP3 inflammasome is important for … to explore whether the NLRP3
inflammasome plays a role in … LAV from CXCR4-preferring HIV-1 isolates because these …

… As HIV-1 Vpr is detectable in the CNS, acts as a … to NLRP3 inflammasome activation in
brain macrophages/microglia, contributing to neuroinflammation. We used the monocytic THP-1 …

… 3 (NLRP3) inflammasome complexes. We evaluated the role of HIV in podocyte NLRP3
inflammasome … Renal cortical sections of HIV-transgenic mice (Tg26) displayed increased …