… group is an established template for Hsp90 inhibition and considering the significant anticancer
activity displayed by imines, we performed docking studies of a series of Schiff bases of 2…

… chemical scaffolds against Hsp90, we performed molecular docking studies using Tripos-…
the required conserved water molecules. The results of the docking studies predicted Mannich …

… In the present study, based on the selected target protein Human Hsp90 (PDB: 1YET), the …
activity through docking and pharmacophore studies. The analyzed results of docking showed …

… , the molecular docking studies were carried out to understand the binding modes of the
Hsp90 protein with 16 training set inhibitors using the Genetic Optimisation for Ligand Docking (…

… In the current study, 3,4-isoxazolediamide derivatives were suggested as an Hsp90 inhibitor
… to build models to predict the inhibitory activity of Hsp90. The leave-one out (LOO) cross-…

… The hit compounds were subsequently subjected to molecular docking studies and, …
inhibition of the Hsp90 folding machinery Citation18. Although docking studies on Hsp90 inhibitors …

… studies and molecular docking studies of various reported inhibitors with HSP90 have shown
… and MAPK driven melanomas are most sensitive to HSP90 inhibitors.13-15 Although the …

… the active site of Hsp90, a molecular docking simulation was … Hsp90 inhibitors in the 3D-QSAR
model. Findings indicate that the predicted ligands were stable in the active site of Hsp90…

… known to be potent inhibitors of HSP90's chaperone activity. The goal of this study is to
generate a 3D pharmacophore models based on the known HSP90 inhibitors, which can …

… effect on Hsp90 enzyme, we utilized MOE 2014.0901 [33] aiming to find a possible fitting …
the Hsp90 reported active site. Molecular modeling inside the active binding site of Hsp90 …