… domain of SARS-CoV-2 (SARS-CoV-2-CTD) spike (S) protein in complex with human ACE2
(… binding mode similar overall to that observed for SARS-CoV. However, atomic details at the …

… -CoV-2) that is causing the serious coronavirus disease 2019 (COVID-19) epidemic. Here,
we present cryo–electron microscopy structures of full-length human ACE2 … ) of SARS-CoV-2, …

… SARS coronavirus (SARS‐CoV). Here we identify the SARS‐CoV spike (S)‐protein‐binding
site on ACE2… S proteins of SARS‐CoV isolated during the 2002–2003 SARS outbreak and …

… Here, we show that clinical grade hrsACE2 reduced SARS-CoV-2 recovery from Vero cells
… that SARS-CoV-2 can directly infect engineered human blood vessel organoids and human …

… by different human ACE2 allelic variants with SARS-CoV-2 spike protein. Briefly, coding
variants of ACE2 corresponding to the reported binding sites for its attachment with coronavirus …

… Because human ACE2 has not evolved to recognize SARS-CoV-2 S, we hypothesized that
mutations may be found that increase affinity. The coding sequence of full-length ACE2 with …

… humans who have been hospitalized. Here, we evaluate transgenic mice expressing the
human angiotensin I-converting enzyme 2 (ACE2… -hACE2) as a model of SARS-CoV-2 infection. …

… In this paper we considered the interaction of S proteins with human ACE2 by combining
coarse-grained and all-atom steered molecular dynamics (SMD) simulations. All-atom models …

… , compared to the one of the Bat-CoV to this receptor. The data presented in … SARS-Cov-2
spike protein to the human ACE2 receptor, compared to the one of Bat-CoV spike and ACE2. …

… involved in the SARS-CoV-2 S-protein interaction. Overall, we found human ACE2 receptor
… and the ACE2 PD showed even more reduced variation (Wilcoxon p-value = 0.0656, n = 65, …