… nucleus RNA expression and chromatin accessibility, DNA … the chromatin landscape and
gene regulation of the kidney in … kidney’s active, silent, and regulatory accessible chromatin …

… To study the open chromatin heterogeneity across cell types … cell type-specific accessible
chromatin landscape by conducting … human kidney cell type-specific open chromatin landscape …

… for use on primary human clinical samples to define the chromatin landscape in a … -kidney-specific
classes of chromatin accessibility changes, as well as those associated with chromatin …

… in the adult mouse kidney has provided a framework for understanding how chromatin
accessibility … , the single-cell epigenomic landscape of the human kidney has not been described. …

… analysis of adult human kidneys by examining cell type-specific chromatin accessibility by
… and DKD human adult kidneys To analyze the chromatin landscape of kidney cell types, we …

… Our results provide a valuable multi-omics resource on the chromatin landscape of human
kidney tubule cells and establish a bioinformatic pipeline in dissecting functions of kidney …

… In general, our findings are consistent with those of recent scRNA-seq studies of human
kidney development (Lindstrom et al., 2018; Menon et al., 2018; Wang et al., 2018) …

… chromatin sequencing (scATAC-seq) to capture the cell type-specific chromatin accessibility
landscape of normal human kidney … profiles of human pRCC samples against the landscape …

… may increase chromatin accessibility to transcription factors and chromatin modifiers, which
… Given that SETD2 is mutated in a wide variety of human cancers, our findings are poised to …

… Interestingly, even though the chromatin landscape is vast, these proteins were all targeted
toward a crowded area of histone H2 and H3 tails. Some of these sites were only a few …