K Rajamäki, J Lappalainen, K Öörni, E Välimäki… - PloS one, 2010 - journals.plos.org
… Here we show that humanmacrophages avidly phagocytose … IL-1β from human monocytes and macrophages. The cholesterol … of an inflammasome-mediated pathway. Silencing of the …
O Lunov, T Syrovets, C Loos, GU Nienhaus… - ACS …, 2011 - ACS Publications
… inflammasomes were not activated by PS-NH 2 . The PS-NH 2 -mediated proinflammatory macrophage … Our study reveals the molecular mechanism of NLRP3inflammasome activation …
… that of the components of Nlrp3inflammasome in LPS-activated macrophages. We have … on humanmacrophage-like THP-1 cells as well as on human monocyte-derived macrophages. …
X Wang, WJ Eagen, JC Lee - Proceedings of the National …, 2020 - National Acad Sciences
… Staphylococcus aureus are internalized by humanmacrophages by an endocytic process, … Macrophages incubated with S. aureus EVs undergo NLRP3inflammasome activation that is …
AM Riestra, JA Valderrama, KA Patras… - Journal of innate …, 2018 - karger.com
… NLRP3inflammasome activation in humanmacrophages, … Using inhibitor-based approaches, we show that NLRP3 activation … vaginalis inflammasome activation induces macrophage in…
… NLRP3inflammasome component in humanmacrophages. NLRP11 bound to ASC and NLRP3 and was required for NLRP3 … In the absence of NLRP11, NLRP3-mediated caspase-1 …
G Camilli, M Bohm, AC Piffer, R Lavenir… - The Journal of …, 2020 - Am Soc Clin Investig
… of β-glucan on NLRP3inflammasome activation in macrophages generated from healthy … NLRP3inflammasome activation in patients with gain-of-function mutations in the NLRP3 gene…
… Our findings reveal that CLCs are recognized by the NLRP3inflammasome, … for NLRP3 inflammasome assembly in vitro and in vivo. Whereas in our in vitro system humanmacrophages …
W Sha, H Mitoma, S Hanabuchi… - Proceedings of the …, 2014 - National Acad Sciences
… the NLRP3inflammasome in humanmacrophages but not in murine macrophages. Therefore, … In this study, we show that humanmacrophages sense all bacterial RNA components (…