… development that has become one of the best-known and most-cited works in the field . The
book summarized a vast amount of renal embryology … establish cell fate and cell number in …

… of human renal disease genes, the molecular bases for many of the early events in the
developing … Induction was permissive rather than instructive: The fate of the mesenchyme was …

… as the renal vesicle stage. The genetic control of proximal-distal nephron cell fate has been
… , transcription factors which are expressed at the renal vesicle stage. Deficiency of Lim1 (…

… The further fate of the nephrogenic lineage is also determined by members of the … are
expressed in renal organogenesis, Pax-2 and Pax-8. Pax-2is central for renal development, since it …

… develop solely a pronephric structure, their development … repressor and directed cell fate
towards kidney rather than … increased vascular cells at the expense of renal progenitor cells.16, …

… (A) Transition of polarized renal vesicle to patterned S-shaped body. (B) Speculative color-encoded
map of the cell fate … Verification requires more extensive cell fate-mapping studies. …

… human subjects with CKD and in mouse models of kidney fibrosis. We found that healthy renal
… Lower FAO by TECs appears to contribute to the development of tubulointerstitial fibrosis (…

… metanephroi can differentiate into mature renal structures with excretory, … human primary
kidney rudiments and can additionally be viewed as a platform to interrogate emerging renal …

… human embryonic stem cells (hESCs) through posterior primitive streak and IM under fully
chemically defined monolayer culture conditions using growth … these alternative fates are not …

… aggregate (PTA), which epithelializes into a renal vesicle (RV) in conjunction with the
parallel branching growth of the adjacent collecting duct network. Morphogenetic processes …