… hygiene-related environmental risk factors and the risk of IBD, where some populations have
and have not supported the hygiene hypothesis. … to support the hygiene hypothesis if the …

… We did not find any support for the hygiene hypothesis. Nonetheless, the relationship
between infection exposures and CD is likely to be more complex and the pattern, type, and …

… The main findings of this work support the “hygiene hypothesis” as a risk factor for IBD.
This association has been extensively proposed for allergic disorders, asthma and various …

… Biological plausibility is one of the greatest strengths of the hygiene hypothesis. The
hypothesis … They conclude that birth order, diet and smoking are the risk factors in the maternal …

… risk factors related to the hygiene hypothesis in our cohort of patients. None of the surrogate
risk factors … On the contrary, as shown in the same table, the well-known risk factors such as …

… In the absence of the Old Friends, not only is immunoregulation inadequately primed, but
also these genetic variants cause excessive inflammation and become risk factors for chronic …

… Conclusion Many of the risk and protective factors we identified are consistent with those …
hygiene hypothesis. Further research on dietary and other environmental and genetic factors is …

… factors can explain the rapid changes observed over the past few decades. A high level of
hygiene has repeatedly been identified as a risk factor for … Interestingly, neither hygienic nor …

… The implications of the original hygiene hypothesis were that the decrease in family size
led to a reduction in the number of childhood infections, which adversely affected immune …

… The hygiene hypothesis is based upon epidemiological data, … Proof of principle of the
hygiene hypothesis is brought by … in favour of the hygiene hypothesis with particular interest on …