SARS-CoV-2–induced Kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in children

F Licciardi, G Pruccoli, M Denina, E Parodi… - …, 2020 - publications.aap.org
… particular, severe acute respiratory syndrome coronavirus 1 causes complement activation
… with a well-known hyper inflammatory syndrome caused in cats by feline coronavirus: feline …

… learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental hyperinflammation

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
… differs from that of previously emerged, SARS-CoV- and MERS-CoV-induced diseases in
its … to severe disease is less for SARS-CoV-2 than for either SARS-CoV or MERS-CoV, the …

Inflammatory syndromes associated with SARS-CoV-2 infection: dysregulation of the immune response across the age spectrum

JE Weatherhead, E Clark, TP Vogel… - The Journal of …, 2020 - Am Soc Clin Investig
… COVID-19–associated hyperinflammatory syndrome within 1 to 2 weeks of exposure to
SARS-CoV-2. COVID-19–associated hyperinflammatory syndrome begins with failure of the …

Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
… innate and adaptive immune responses against SARS-CoV-2 infection. Cytokine …
SARS-CoV and MERS-CoV infections culminating in severe lung fibrosis, often with poor disease

… of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated With SARSCoV‐2 and hyperinflammation in pediatric COVID‐19 …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2020 - Wiley Online Library
… related to MIS-C and hyperinflammation in COVID-19 were … of MIS-C and hyperinflammation
in pediatric COVID-19. These … Our understanding of SARSCoV-2–related syndromes in …

… of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARSCoV‐2 and Hyperinflammation in pediatric COVID‐19 …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2021 - Wiley Online Library
… of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection. …
hyperinflammation during coronavirus disease 2019 (COVID-19), the acute, infectious phase of …

… of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARSCoV‐2 and hyperinflammation in pediatric COVID‐19 …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2022 - Wiley Online Library
Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

[HTML][HTML] Colchicine and SARS-CoV-2: management of the hyperinflammatory state

A Vitiello, F Ferrara - Respiratory Medicine, 2021 - Elsevier
… , a generalized hyperinflammatory state causing … hyperinflammatory state is caused by a
sudden release of cytokines into the circulation referred to as a “cytokine storm” [3,4]. SARS-CoV

Can beta-2-adrenergic pathway be a new target to combat Sars-Cov-2 hyperinflammatory syndrome?—lessons learned from cancer

A Barbieri, N Robinson, G Palma, N Maurea… - Frontiers in …, 2020 - frontiersin.org
… of the disease toward stage III. The key event leading to hyperinflammation seems to be
the … witnessed two novel types of coronavirus, severe acute respiratory syndrome CoV (SARS-…

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

MH Cheng, S Zhang, RA Porritt… - Proceedings of the …, 2020 - National Acad Sciences
… that the hyperinflammatory syndrome originates from superantigenic activity by SARS-CoV-…
Furthermore, these findings also raise the possibility that the hyperinflammation observed in …