… to type I IFN. In this study, we examined the antiviral potential of exogenous human IFN-λ1 in
cellular … To study the protective effects of IFN-λ1, three administration schemes were used: ‘…

… of viruses induce expression of IFN-λ1 and -λ2/3 in similar patterns. The … antiviral activity
of IFN-λ in vitro. In addition, we have evaluated the antiviral activity of recombinant IFN-λ in vivo …

… We also assayed the antiviral activity of IFN-β, IFN-λ1, and oseltamivir carboxylate by virus
yield reduction assay, which allows detection of the extracellular virus yield in cell culture …

… No data concerning type III IFNs antiviral activity against CCHFV are … of IFN-λ1 to inhibit
the replication of CCHFV and the possible synergism/antagonism between IFN-α and IFN-λ1 …

… Humans and chickens have three IFN-λs as follows: IFN-λ1 (IL-29), IFN-λ2 (IL-28A), and
IFN-… possesses antiviral activity against PEDV in a dose- and time-dependent manner in vitro, …

… Interferon lambda (IFN-λ) is a recently discovered group of small helical cytokines capable of
inducing an antiviral response both in vitro as well as in vivo… the antiviral activities of IFN-λ1, …

… There are three members of this group, IFN-λ1–3 or IL-28A/B and IL-29, and they signal …
-28RA −/− mice and investigated the role of IFN-λ in antiviral defense in vivo. We report that …

… Supernatants were used to measure IL-6, IL-8 and IFN-λ1/3 levels using paired antibodies
and standards (R&D Systems for IL-6/IL-8 and Duoset kit from R&D Systems for IFN-λ1/3). …

… Although there are three genes encoding closely related but distinct human IFN-λs (IFN-λ1,
IFN-λ2 and IFN-λ3), the search revealed the existence of only two intact mouse genes, …

… IFN-λ was reported to induce in vitro marked antiviral activity … Therefore we examined the
IFN-λ1 induced antiviral activity … The antiviral response was determined in vitro in Vero cells, …