Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
… knowledge of host immune dysregulation during infection … immunopathological host
response and the mechanistic role of viral proteins in the active manipulation of the host immune

Immune dysregulation and system pathology in COVID-19

M Jamal, HI Bangash, M Habiba, Y Lei, T Xie, J Sun… - Virulence, 2021 - Taylor & Francis
… T cells are the frontline defender to control viral infections and a dysregulated T cell immune
response may lead to immunopathology and ultimately result in severe disease outcome. …

The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
… Here we review the data of the immune response during COVID-19 infection. The current
review summarizes our understanding of how immune dysregulation and altered cytokine …

Flow cytometry contributions for the diagnosis and immunopathological characterization of primary immunodeficiency diseases with immune dysregulation

O Cabral-Marques, LF Schimke… - Frontiers in …, 2019 - frontiersin.org
… , including patients with symptoms of immune dysregulation. This tool can identify not …
immune dysregulation and its contributions for a better understanding of disease immunopathology

[HTML][HTML] An innate checkpoint determines immune dysregulation and immunopathology during pulmonary murine coronavirus infection

S Grabherr, A Waltenspühl, L Büchler… - The Journal of …, 2023 - journals.aai.org
… include dysregulated antiviral immunity and immunopathological … regulating anticoronavirus
immunity and preservation of tissue … of coronavirus dissemination and immunopathology. …

Dysregulation of the cytokine GM-CSF induces spontaneous phagocyte invasion and immunopathology in the central nervous system

S Spath, J Komuczki, M Hermann, P Pelczar, F Mair… - Immunity, 2017 - cell.com
… While GM-CSF is clearly necessary for the development of immunopathology in inflammation,
the pathophysiological consequences of dysregulated GM-CSF expression alone are …

Immune evasion, immunopathology and the regulation of the immune system

G Sorci, S Cornet, B Faivre - Pathogens, 2013 - mdpi.com
… regulated immune system. In this article, we suggest that the maintenance of immunopathology
… : (i) the trade-off between immunoprotection and immunopathology and (ii) the strategies …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
… a dysregulated host innate immune response… immune system in the immunopathology of
COVID-19. Indeed, the efficacy of several immunomodulatory agents in attenuating the immune

Immune dysregulation in the functional gastrointestinal disorders

S Keely, MM Walker, E Marks… - European journal of …, 2015 - Wiley Online Library
… Here, we discuss the current knowledge of immune involvement in FGIDs and the … a new
hypothesis, potentially defining an underlying immunopathological basis of these conditions. …

A basic overview of multiple sclerosis immunopathology

N Grigoriadis, V Van Pesch - European journal of neurology, 2015 - Wiley Online Library
Immune dysregulation in MS The immune dysregulation in MS is considered to be multifactorial,
… The immune dysregulation in MS involves ‘crosstalk’ between the innate and adaptive …