[HTML][HTML] Evolution of enhanced innate immune evasion by SARS-CoV-2

LG Thorne, M Bouhaddou, AK Reuschl… - Nature, 2022 - nature.com
COVID-19 outcomes 8,9,10 . We hypothesized that the Alpha variant evolved enhanced innate
immune … first-wave (early-lineage) SARS-CoV-2 induce a delayed innate response, which …

[HTML][HTML] Immune evasion of SARS-CoV-2 emerging variants: what have we learnt so far?

I Lazarevic, V Pravica, D Miljanovic, M Cupic - Viruses, 2021 - mdpi.com
… Despite the slow evolutionary rate of SARS-CoV-2 relative to other RNA viruses, its massive
… patterns, and the role mutations play in immune evasion are summarized in this review. …

Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein

TG Flower, CZ Buffalo, RM Hooy… - Proceedings of the …, 2021 - National Acad Sciences
… These observations show how recent evolutionary changes in the sequence of SARS-CoV-2
higher-order assembly mediating unique functions in immune evasion and suppression. …

[HTML][HTML] The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
… and immune evasion. This Review explores the mechanisms that generate genetic variation
in SARS-CoV-2, … We examine the selective forces that likely drove the evolution of higher …

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution

W Ma, H Fu, F Jian, Y Cao, M Li - Nature Ecology & Evolution, 2023 - nature.com
… suggest that immune evasion and ACE2 binding affinity play significant and diverse roles in
the evolution of SARS-CoV-2. … evolutionary analysis of SARS-CoV-2 from the perspective of …

Evolution of SARS-CoV-2: review of mutations, role of the host immune system

H Banoun - Nephron, 2021 - karger.com
… [26] highlight the importance of deletions in immune evasion on the evolutionary trajectory
of SARS-CoV-2 to an endemic virus. According to Parvez et al. [27] and Rahman et al. …

[HTML][HTML] Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
… of infection and provide time for the adaptive immune response to develop the capacity for …
barrier to the evolutionary success of any virus. Unfortunately, viruses have evolved countless …

[HTML][HTML] Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
… the immunological response and clinical outcome in humans. This review systematically
describes the evolutionary and molecular characteristics of SARS-CoV-2 … of immune evasion of …

[HTML][HTML] Evolutionary and structural analysis of SARS-CoV-2 specific evasion of host immunity

I Hussain, N Pervaiz, A Khan, S Saleem, H Shireen… - … & Immunity, 2020 - nature.com
… The 3′-terminus of the SARS-CoV-2 genome encodes for … The availability of SARS-CoV-2
genome sequence data has … the evolutionary origin and phylogenetics of SARS-CoV-2 with …

[HTML][HTML] Fast evolution of SARS-CoV-2 BA. 2.86 to JN. 1 under heavy immune pressure

S Yang, Y Yu, Y Xu, F Jian, W Song… - The Lancet Infectious …, 2024 - thelancet.com
… We first study the humoral immune evasion of JN.1 using pseudovirus-based neutralisation
assays with plasma from individuals recovering after XBB infection. These individuals, …