The site on HIV-1 gp120 that binds to the CD4 receptor is vulnerable to antibodies. However,
most antibodies that interact with this site cannot neutralize HIV-1. To understand the basis …

… determined their structures by cryo–electron microscopy (cryo-EM), providing a structural
basis for … mechanisms of the enhanced infectivity of B.1.1.7 and the immune evasion of B.1.351. …

… This work defines the molecular basis for the broad evasion of humoral immunity exhibited
by SARS-CoV-2 Omicron and underscores the SARS-CoV-2 S mutational plasticity as well as …

… innate immune responses that would otherwise facilitate clearance of the infection. Thus,
the structural characterization of the inhibitory mechanism of Nsp1 may aid structure-based …

… To explore the structural basis for dsRNA binding and specificity of mVP35, we solved the
crystal structure of mIID in complex with 18-bp dsRNA to 2.01-Å resolution (see Fig. 1 and …

… to constrain bacterial immune escape (fig. S17). Although many pathogens do at least partially
evade innate immunity, our results suggest that evasion of innate immunity likely involves …

… structural basis of assembly of the Gabija anti-phage defence complex and define a unique
mechanism of viral immune evasion… Our study defines the structural basis of the formation of …

… the virus to efficiently evade recognition by specific CD8 + T cells. Analysis of the structures
of gp33 bound to both class I molecules suggests a structural basis for these escape …

The HIV-1 protein Nef inhibits antigen presentation by class I major histocompatibility complex
(MHC-I). We determined the mechanism of this activity by solving the crystal structure of a …

… In this study, we focus on finding the molecular basis of immune evasion by the Omicron
variant, as it is already known to infect the previously infected as well as vaccinated population. …