[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… Here, we discuss recent progress in innate immunity and inflammatory cell death, providing
insights into the cellular and molecular mechanisms of CSs and therapeutics that might quell …

[HTML][HTML] … cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Cytokine storm is an extremely deadly immune disorder characterized by abrupt … over 150
chemical mediators and inflammatory cytokines by non-immune as well as immune cells [36,37…

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… innate immune cells, resulting in cytokine storms. Collectively, the impaired acquired immune
… uncontrolled inflammatory innate responses to SARS-CoV-2 may cause cytokine storms. …

The advent of the cytokine storm

IA Clark - Immunology and cell biology, 2007 - search.proquest.com
The term ‘cytokine storm’is now used in popular culture as an explanation for the distinctly
unpleasant feeling we all sense at the onset of flu. The expression certainly has common …

[HTML][HTML] Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
cytokine storms induced by COVID-19, as well as potential intervention strategies to control
cytokine storms. … , among which the pro-inflammatory cytokines could promote more immune

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… with profiles of cytokines released during cytokine storm varying … mechanisms underlying
cytokine storm induction and … If cytokine storm occurs, the body’s immune system will …

[HTML][HTML] Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19

FH Pottoo, T Abu-Izneid, AM Ibrahim, MN Javed… - Saudi pharmaceutical …, 2021 - Elsevier
… of “immunocytokines” resulting in cytokine storm (CS); … cytokine storm are now being
considered as a new paradigm shift in the clinical management of SARS-CoV-2. Tocilizumab (IL-6

New fronts emerge in the influenza cytokine storm

XJ Guo, PG Thomas - Seminars in immunopathology, 2017 - Springer
cytokines and introduce several new members into the storm, including IL-33 and amphiregulin,
whose functions are … , and functions of the cytokines in influenza immune responses to …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… ) and adaptive cellular immunity (blood … cytokine storm versus an immunosuppressive
immunological endotype, and determine whether there are changes in immune function during …

Immune-mediated cytokine storm and its role in severe dengue

A Srikiatkhachorn, A Mathew, AL Rothman - Seminars in …, 2017 - Springer
… DENV is introduced through mosquito bites and infects local immune cells … Cytokines
produced by these local immune cells regulate viral replication and further recruit immune cells to …