Cytokine storm mitigation for exogenous immune agonists

I Kareva, JL Gevertz - Mathematics of Control, Signals, and Systems, 2024 - Springer
… , cytokine storms, or hypercytokinemia, where the immune … prominent cytokines that are
elevated during cytokine storms … More generally, cytokine storms appear to reflect a scenario …

[PDF][PDF] Cytokine storm syndrome in COVID-19: diagnosis and management strategies

S Maggo, P Dhull, AP Dubey, D Brashier… - Int J Health Sci …, 2020 - researchgate.net
… disease to severe is immune dysfunction and cytokine dysregulation resulting in what is
called as “cytokine storm syndrome”. It is prudent to diagnose cytokine storm early in the course …

On the alert for cytokine storm: immunopathology in COVID‐19

LA Henderson, SW Canna, GS Schulert… - Arthritis & …, 2020 - Wiley Online Library
… the umbrella of cytokine storm syndrome, in which hyperinflammation and multiorgan disease
arise through excessive cytokine release from uncontrolled immune activation (Figure 1). …

Cytokine storm and targeted therapy in hemophagocytic lymphohistiocytosis

H Zhang, SW Yang, YC Fu, MC Chen, CH Yang… - Immunologic …, 2022 - Springer
… The current initial treatment for HLH aims to suppress the excessive activation of the
immune system and treat the cytokine storm [12]. According to the HLH-2004 treatment plan, …

Interferon lambdas: the next cytokine storm

C Kelly, P Klenerman, E Barnes - Gut, 2011 - gut.bmj.com
… risk allele identified in the GWAS affect immune function or exert specific antiviral effects in
HCV-… Currently, this assessment can only be made indirectly by observing immune function or …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… levels in severe cases, leading to an inflammatory cytokine storm, yet leaving the immune
system unimpeded to move toward a general resolution of the antiviral response appears in …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
… -2) and its relationship with the host cytokine storm. Furthermore, the proposed therapeutic
immune responses can enhance host immunity against infection, while excessive immune

Cytokine storms: systemic disasters of infectious diseases

A Nazinitsky, KS Rosenthal - Infectious Diseases in Clinical …, 2010 - journals.lww.com
… This article will review the cytokine storm that results from overstimulation of innate and
immune responses by bacterial components, sepsis, superantigens, toxins, and viruses. …

The meteorology of cytokine storms, and the clinical usefulness of this knowledge

IA Clark, B Vissel - Seminars in immunopathology, 2017 - Springer
… the phenomenon of a cytokine storm, we have … cytokine storm is about dramatic illness and
disease, these mediators also have essential roles in normal physiology and innate immunity. …

The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
… (ARDS) appears to be a virally-induced over-activation or unregulated response of the
immune system, termed a “cytokine storm,” featuring elevated levels of pro-inflammatory …