The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity

H Bolouri, C Speake, D Skibinski… - The Journal of …, 2021 - Am Soc Clin Investig
… and classified based on maximal disease severity. Hospitalized patients negative for … immune
landscape in COVID-19 formed 3 dominant clusters, which correlated with disease severity

Understanding the immune landscape in atopic dermatitis: The era of biologics and emerging therapeutic approaches

M Moyle, F Cevikbas, JL Harden… - Experimental …, 2019 - Wiley Online Library
disease severity.54-57 Of note, IL-22 and the type 17-specific cytokine, IL-17, upregulate
expression of certain S100 epidermal differentiation proteins including S100A7, S100A8 and …

[HTML][HTML] On deep landscape exploration of COVID-19 patients cells and severity markers

A Vázquez-Jiménez, UE Avila-Ponce De Leon… - Frontiers in …, 2021 - frontiersin.org
… the differences of these cells, characterizing the immune landscape during infection (1–5). …
section we survey possible genetic biomarkers of the disease severity. To this aim, we applied …

Immune cell landscaping reveals distinct immune signatures of inflammatory bowel disease

X Bai, W Liu, H Chen, T Zuo, X Wu - Frontiers in Immunology, 2022 - frontiersin.org
… However, the exact alterations in the immune landscape … of immune cell landscapes in
intestinal tissues may shed light on new therapeutic targets in IBD that can be tailored to disease

Immune response in severe and non-severe coronavirus disease 2019 (COVID-19) infection: a mechanistic landscape

K Mukund, P Nayak, C Ashokkumar, S Rao… - Frontiers in …, 2021 - frontiersin.org
The mechanisms underlying the immune remodeling and severity response in coronavirus
disease 2019 (COVID-19) are yet to be fully elucidated. Our comprehensive integrative …

The immune landscape in tuberculosis reveals populations linked to disease and latency

E Esaulova, S Das, DK Singh, JA Choreno-Parra… - Cell host & …, 2021 - cell.com
diseases such as TB. Therefore, in the present study, we have probed the immune landscape
in NHPs … Our discoveries about the immune landscape of TB latency and disease show the …

A regulatory T cell signature distinguishes the immune landscape of COVID-19 patients from those with other respiratory infections

SC Vick, M Frutoso, F Mair, AJ Konecny, E Greene… - Science …, 2021 - science.org
… We also acknowledge that the different sampling time frames after infection or after symptom
onset, as well as differing classifications of disease severity could account for differences in …

Immune landscape of CMV infection in cancer patients: from “canonical” diseases toward virus-elicited oncomodulation

R El Baba, G Herbein - Frontiers in immunology, 2021 - frontiersin.org
… This review accentuates the considerable influence of HCMV on the immune landscape
Figure 2 Major signaling pathways stimulated by HCMV that modulate the immune landscape. …

Germline genetic contribution to the immune landscape of cancer

RW Sayaman, M Saad, V Thorsson, D Hu, W Hendrickx… - Immunity, 2021 - cell.com
… Understanding the contribution of the host’s genetic background to cancer immunity may …
We investigated the effect of common and rare germline variants on 139 well-defined immune

Current genetic landscape in common variable immune deficiency

H Abolhassani, L Hammarström… - Blood, The Journal …, 2020 - ashpublications.org
… underlying severe combined immune deficiency, could also produce milder CVID-like
defects. More recently, an increasing number of autosomal-dominant (AD) immune defects that …