The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… innate immune cells, resulting in cytokine storms. Collectively, the impaired acquired immune
responses and … inflammatory innate responses to SARS-CoV-2 may cause cytokine storms. …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… Here, we discuss recent progress in innate immunity and inflammatory cell death, providing
… new insights into fine-tuning immune responses to treat these life-threatening conditions. …

[HTML][HTML] Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19

FH Pottoo, T Abu-Izneid, AM Ibrahim, MN Javed… - Saudi pharmaceutical …, 2021 - Elsevier
immune response and elevated production of “immunocytokines” resulting in cytokine storm
… Hence attempts to reduce cytokine storm are now being considered as a new paradigm shift …

Is a “cytokine storm” relevant to COVID-19?

P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
… However, on the other hand, hypercytokinenemia due to dysregulated immune response or
cytokine storm syndrome can lead to pulmonary and non-pulmonary organ damage that may …

[HTML][HTML] Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy

Y Jiang, L Rubin, T Peng, L Liu, X Xing… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
cytokines can trigger an uncontrolled immune response, damage lung tissue, and develop
into multiorgan failure 10 , 11 . Therefore, suppression of the cytokine storm … of cytokine storm

[HTML][HTML] Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Cytokine Storm and Cytokine Release Syndrome The cytokine storm, previously reported
in … ), has been used to describe the overactive immune responses that can be triggered by a …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
immune responses may improve outcome. We review some of the current candidates for
treatment of cytokine storms … candidates that target the pathogen rather than the host response. …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… Failure of the initial immune response by type-1 IFNs increases excessively the … immune
system leading to cytokine storm. Aerosolized type-1 IFNs promotes an initial immune response

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… “cytokine storm” calls up vivid images of an immune system gone awry and an inflammatory
response … We still do not understand the complex nature of the immune response and have …

[HTML][HTML] Dynamics of a cytokine storm

HH Yiu, AL Graham, RF Stengel - 2012 - journals.plos.org
… insight into the course and impact of immune-mediated cytokine storms. The analysis presented
here … concentrations are driven not only by TGN1412 and immune response but also by …