Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

NAF Janssen, I Grondman… - … infectious diseases, 2021 - academic.oup.com
Disease severity was defined according to the patient’s need for intensive care at the time
of plasma sampling (critical in ICU vs severe … representation of disease severity in our study …

Age‐related differences in the immune response could contribute to determine the spectrum of severity of COVID‐19

G Costagliola, E Spada… - Immunity, inflammation …, 2021 - Wiley Online Library
… impact in determining the spectrum of severity of COVID‐19. … contribute to disease severity
through immune‐mediated … susceptibility to develop an immune dysregulation following SARS…

How do inflammatory mediators, immune response and air pollution contribute to COVID-19 disease severity? A lesson to learn

C Signorini, P Pignatti, T Coccini - Life, 2021 - mdpi.com
… Inflammatory and immune processes are defensive … As a response to infections,
inflammation and immune response contribute to the pathophysiological mechanisms of diseases. …

[HTML][HTML] Immune responses to Leptospira infection: roles as biomarkers for disease severity

C Chirathaworn, S Kongpan - Brazilian Journal of Infectious Diseases, 2014 - SciELO Brasil
… to leptospires have been implicated in target organ damages in severe … for disease severity
in human leptospirosis. This review focuses on the role of immune responses in the severity

[HTML][HTML] Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li… - Gut, 2021 - gut.bmj.com
… microbiota are known to modulate host immune responses,12 we hypothesised that … immune
responses in COVID-19. Here, we characterised the gut microbiota and immune response

[HTML][HTML] Viral load and humoral immune response in association with disease severity in Puumala hantavirus-infected patients—implications for treatment

L Pettersson, T Thunberg, J Rocklöv… - Clinical Microbiology …, 2014 - Elsevier
disease severity. We conclude that a low specific IgG response was associated with disease
severity in patients with HFRS, whereas PUUV RNA load did not seem to affect the severity

COPD disease severity and innate immune response to pathogen-associated molecular patterns

VS Fan, SA Gharib, TR Martin… - … pulmonary disease, 2016 - Taylor & Francis
severity. We sought to better understand the relationship between COPD severity and innate
immune responses to … production in peripheral whole blood increases with disease severity. …

Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression

MC Dubinsky, YC Lin, D Dutridge… - Official journal of the …, 2006 - journals.lww.com
… is often described as having a more severe disease phenotype; ie, an aggressive or …
immune responses to microbial antigens may be a more direct determinant or indicator of disease

Immune responses in acute and convalescent patients with mild, moderate and severe disease during the 2009 influenza pandemic in Norway

KGI Mohn, RJ Cox, G Tunheim, JE Berdal, AG Hauge… - PloS one, 2015 - journals.plos.org
… humoral and cellular immune responses. Those … disease severities (mild, moderate or
severe). In general, protective antibody responses increased with enhanced disease severity. In …

… intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and …

CP Simmons, GE Thwaites, NTH Quyen… - The Journal of …, 2006 - journals.aai.org
… We hypothesized that an excessive intracerebral inflammatory immune response would be
Immune responses in HIV-negative and HIV-positive patients were analyzed separately. …