Immune profiles provide insights into respiratory syncytial virus disease severity in young children

S Heinonen, VM Velazquez, F Ye, S Mertz… - Science translational …, 2020 - science.org
immune response plays a major role in determining disease … children spanning the disease
severity spectrum and across … RSV replication, the innate immune response, and age. …

The immune response in inflammatory bowel disease

SJ Brown, L Mayer - Official journal of the American College of …, 2007 - journals.lww.com
immune response in the normal bowel, have led to unifying hypotheses regarding the
pathogenesis. An inappropriate mucosal immune response … Patients with moderate-to-severe UC …

Host resistance and immune responses in advanced age

SC Castle, K Uyemura, T Fulop, T Makinodan - Clinics in geriatric medicine, 2007 - Elsevier
… Grouping individuals by disease severity or by level of impairment of specific components
of … immune responses. The specificity and regulation of the acquired immune response is …

HL-A, immune-response genes, and disease

HO Mcdevitt, WF Bodmer - The Lancet, 1974 - Elsevier
immune response, and disease severity. Their data also suggested that the association
with an HL-A haplotype was specific for antibodies to ragweed allergen, and not for reaginic …

Different innate and adaptive immune responses to SARS-CoV-2 infection of asymptomatic, mild, and severe cases

R Carsetti, S Zaffina, E Piano Mortari, S Terreri… - Frontiers in …, 2020 - frontiersin.org
… the basis of the protective immune response in COVID-19, we … analysis of innate and
adaptive immunity in 64 adults with a … of disease severity suggests that the individual immune

Analysis of humoral immune responses in patients with severe acute respiratory syndrome coronavirus 2 infection

L Henss, T Scholz, C von Rhein… - … Infectious Diseases, 2021 - academic.oup.com
… The severity of COVID-19 increased with age, and male patients encountered more serious
symptoms than female patients. Disease severity … , COVID-19 disease severity seemed to be …

Functional and immune response to respiratory syncytial virus infection in aged BALB/c mice: a search for genes determining disease severity

RA Mosquera, JM Stark, CL Atkins… - Experimental Lung …, 2014 - Taylor & Francis
… Despite this “immune priming” RSV continues to cause severe diseases in the elderly. The
immune response to RSV in our mouse model and to provide clues to the enhanced severity

Decreased innate immune cytokine responses correlate with disease severity in children with respiratory syncytial virus and human rhinovirus bronchiolitis

C García, A Soriano-Fallas, J Lozano… - … infectious disease …, 2012 - journals.lww.com
immune response were specific, if at all, in children infected with RSV or HRV and, if they had
any associations with clinical disease severity. … enhanced innate immune response to RSV …

Association of human immune response to Aedes aegypti salivary proteins with dengue disease severity

C MACHAIN‐WILLIAMS, MP Mammen Jr… - Parasite …, 2012 - Wiley Online Library
… because of modulation of the host immune response (12–15). … In experimental models,
disease severity was reduced in … human immune response to MSP and DEN disease severity. …

Immune responses during COVID-19 infection

C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
… Paradoxically, exacerbated or uncontrolled induction of these pro-inflammatory cytokines
can also increase pathogenesis and disease severity as described for SARS-CoV and MERS-…