Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology

G Sturm, F Finotello, F Petitprez, JD Zhang… - …, 2019 - academic.oup.com
… computational cell type quantification methods for immuno-oncology at a per-cell-type
resolution… benchmark on methods that provide cell-type signatures for immuno-oncology (Table 1). …

Immuno-oncology combinations: a review of clinical experience and future prospects

SJ Antonia, J Larkin, PA Ascierto - Clinical Cancer Research, 2014 - AACR
… of death receptors or “distress” ligands, reducing expression of prosurvival signals, abrogating
the production of tumorigenic inflammation, and inhibiting immunosuppressive cell types (…

Multiomic analysis of cytokines in immuno-oncology

V Jurisic - Expert review of proteomics, 2020 - Taylor & Francis
… produced by different cell types including cancer cells and various subpopulations of …
approach to immuno-oncology this paper discusses the multiple roles of cytokines in oncology and …

Single-cell analysis in immuno-oncology

MI Christodoulou, A Zaravinos - International Journal of Molecular …, 2023 - mdpi.com
… The TME is an intricate environment containing different cellular types that can be separated
at a single level and processed without further management. scRNA-seq allows us to …

[HTML][HTML] Current markers and their value in the era of immuno-oncology

FC von Rundstedt, A Necchi - Translational andrology and urology, 2017 - ncbi.nlm.nih.gov
type of Immunotherapy in oncology is the stimulation of the patient’s own immune system to
attack cancer cells… He introduced the idea of stimulating the immune system by administering …

[HTML][HTML] Comprehensive analysis of the clinical immuno-oncology landscape

J Tang, A Shalabi, VM Hubbard-Lucey - Annals of Oncology, 2018 - Elsevier
… Advances from immuno-oncology (IO) are changing the standard of care of many types of …
into six categories: (i) T-cell-targeted immunomodulators that act on inhibitory or activating …

[HTML][HTML] Melanoma as a model tumour for immuno-oncology

M Maio - Annals of Oncology, 2012 - Elsevier
… the cutting edge of immuno-oncology research and will likely … immuno-oncology and to inform
development in other typescells derived from melanocytes but not other cell types; cancer …

Trends in the global immuno-oncology landscape.

J Tang, L Pearce, J O'Donnell-Tormey… - Nat. Rev. Drug …, 2018 - nature.com
… quickly become the standard of care for many cancer types. … survey of the global
immuno-oncology (IO) landscape in … of cell therapies in a year, CD19-targeted cell therapies only …

Targeting T cell activation in immuno-oncology

SD Saibil, PS Ohashi - Current Oncology, 2020 - mdpi.com
… of all of those suppressive cell types in tumour biology and in peripheral tolerance. It is clear
that multiple immune cell populations of the innate immune system can regulate the immune …

Cancer Immunoediting in the Era of Immuno-oncology

MM Gubin, MD Vesely - Clinical Cancer Research, 2022 - AACR
… of several immune cell populations (eg, T cells, NK cells) and molecules (eg, type I and type
II … and human patients with cancer with additional cell types and molecules having also been …