SARS-CoV-2 in immunocompromised individuals

S DeWolf, JC Laracy, MA Perales, M Kamboj… - Immunity, 2022 - cell.com
Immunocompromised individuals and particularly those with hematologic malignancies
are at increased risk for SARS-CoV-2-associated morbidity and mortality due to immunologic …

Monitoring and managing SARS-CoV-2 evolution in immunocompromised populations

P Li, AC de Vries, N Kamar, MP Peppelenbosch… - The Lancet …, 2022 - thelancet.com
… that SARS-CoV-2 infection in immunocompromised populations might propagate SARS-CoV-2 …
Immunocompromised populations include a variety of subpopulations, such as organ …

[HTML][HTML] Case study: prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer

VA Avanzato, MJ Matson, SN Seifert, R Pryce… - Cell, 2020 - cell.com
… Here we describe an asymptomatic, immunocompromised individual persistently testing
positive for SARS-CoV-2 by qRT-PCR who was infected during the early phase of SARS-CoV-2 …

The duration of infectiousness of individuals infected with SARS-CoV-2

KA Walsh, S Spillane, L Comber, K Cardwell… - Journal of Infection, 2020 - Elsevier
… For another 5 studies, SARS-CoV-2 was isolated … ; SARS-CoV-2 was isolated up to
day 32 in one study. Two studies identified immunocompromised patients from whom SARS-CoV-2 …

SARS-CoV-2 viral dynamics in immunocompromised patients

S Caillard, I Benotmane, GG Vargas… - American Journal of …, 2021 - amjtransplant.org
immunocompromised patients are not yet available. Here, we prospectively monitored the
dynamic change in SARS-CoV-… SARS-CoV-2 in accordance with the WHO technical guidance. …

[HTML][HTML] SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

SA Clark, LE Clark, J Pan, A Coscia, LGA McKay… - Cell, 2021 - cell.com
… Many individuals mount nearly identical antibody responses to SARS-CoV-2. To gain …
virus evolution in a persistently infected immunocompromised individual. We use antibody Fab/…

The immunocompromised transplant recipient and SARS-CoV-2 infection

JA Fishman - Journal of the American Society of Nephrology, 2020 - journals.lww.com
… We assume that, for each pathogen, the immunocompromised host will demonstrate reduced
resistance to infection, atypical clinical signs and symptoms, more rapid progression, and …

[HTML][HTML] Transmissibility and viral replication of SARSCOV‐2 in immunocompromised patients

A Beran, E Zink, M Mhanna… - Journal of Medical …, 2021 - ncbi.nlm.nih.gov
… infectiousness and shedding of SARSCoV‐2 in the immunocompromised patients is scarce,
… regarding transmissibility and replication of SARSCoV‐2 in immunosuppressed patients. …

[HTML][HTML] Prolonged viral shedding of SARS-CoV-2 in an immunocompromised patient

Y Nakajima, A Ogai, K Furukawa, R Arai, R Anan… - Journal of Infection and …, 2021 - Elsevier
… Even though it has been reported that the viral burden of SARS-CoV-2 measured in upper
… We report a case of immunocompromised patient with malignant lymphoma, who had …

Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany

B Jensen, N Luebke, T Feldt, V Keitel… - The Lancet Regional …, 2021 - thelancet.com
… After identifying immunocompromised patients with viral rebound under treatment with
bamlanivimab, we characterized the SARS-CoV-2-isolates by whole genome sequencing. Viral …