Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled …

MG Johnson, JM Strizki, ML Brown, H Wan… - Infection, 2023 - Springer
… cohort of molnupiravir-treated immunocompromised participants were not at unique locations
compared to molnupiravir- or placebo-treated non-immunocompromised participants. This …

Molnupiravir efficacy among immunocompromised patients with COVID-19: no proof of concept

D Guermazi, P Arvanitis, D Farmakiotis - Infection, 2023 - Springer
… We read with interest the study “Molnupiravir for the treatment of COVID-19 in
immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, …

Vaccines and therapeutics for immunocompromised patients with COVID-19

S Shoham, C Batista, YB Amor, O Ergonul… - …, 2023 - thelancet.com
… and treatment approaches in immunocompromised people … included very few
immunocompromised participants. While … care arm could even receive molnupiravir. Although no …

[HTML][HTML] Antiviral combination therapies for persistent COVID-19 in immunocompromised patients.

D Focosi, F Maggi, A D'Abramo, E Nicastri… - International Journal of …, 2023 - Elsevier
… -analysis (including 3 RCTs enrolling 1487 participants and 5 controlled studies) CCP was
… Combination regimen of nirmatrelvir/ritonavir and molnupiravir for the treatment of persistent …

Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
Molnupiravir was safe during the study period in outpatients although … routine use of
molnupiravir for COVID-19 treatment in … participants was only about 6% and 9% in molnupiravir

Molnupiravir Outpatient Treatment for Adults with COVID-19 in a Real-World Setting—A Single Center Experience

K Czarnecka, P Czarnecka, O Tronina… - Journal of Clinical …, 2022 - mdpi.com
… Conclusion: Molnupiravir may be perceived as an alternative treatment for patients with
immunosuppression … All the study participants completed a full course of molnupiravir treatment. …

Immunocompromised patients and COVID-19: how do we protect those most at risk?

J Schneider, J Erber, L Renders… - Expert Review of Anti …, 2024 - Taylor & Francis
… for molnupiravir, arguing that the available data did not demonstrate the clinical benefit of
molnupiravir in treating … for the treatment of COVID-19 in non-hospitalized participants is still …

Molnupiravir as an early treatment for COVID-19: a real life study

M Pontolillo, C Ucciferri, P Borrelli, M Di Nicola… - Pathogens, 2022 - mdpi.com
… , with a reduction in CRP after antiviral treatment. In addition, in Johnson’s study of the safe
population, participants who received molnupiravir had earlier and larger reductions in mean …

… therapy with 2 antivirals and monoclonal antibodies for persistent or relapsed severe acute respiratory syndrome coronavirus 2 infection in immunocompromised …

M Mikulska, C Sepulcri, C Dentone… - Clinical Infectious …, 2023 - academic.oup.com
… of molnupiravir and nirmatrelvir/r showed increased activity [10, 11], as did combined treatment
with molnupiravir … In the trial of early treatment with tixagevimab/cilgavimab, 4 participants

Nirmatrelvir/ritonavir and molnupiravir in the treatment of mild/moderate COVID-19: results of a real-life study

I Gentile, R Scotto, N Schiano Moriello, B Pinchera… - Vaccines, 2022 - mdpi.com
… All participants in the trial were not vaccinated. … immunodeficiency mostly related to active
hematological disease and immunosuppressant treatment (49.3% in the molnupiravir group, …