Association of Molnupiravir and Nirmatrelvir-Ritonavir with reduced mortality and sepsis in hospitalized omicron patients: A territory-wide study

AK Wai, TT Lee, SC Chan, CY Chan, ET Yip, LY Luk… - Scientific Reports, 2023 - nature.com
… older adults, and immunosuppressed individuals 15 , especially … into the Molnupiravir and
Nirmatrelvir-Ritonavir treatment groups… , as participants were censored at first event of interest. …

Early clinical experience with molnupiravir for mild to moderate breakthrough COVID-19 among fully vaccinated patients at risk for disease progression

A Vena, L Traman, M Bavastro, A Limongelli… - Vaccines, 2022 - mdpi.com
… 19, the percentage of unvaccinated participants who had been … phase, primary or acquired
immunodeficiency), which have … not treated with oral antiviral medications, we believe that …

Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among high-risk …

AKC Wai, CY Chan, AWL Cheung, K Wang… - The Lancet Regional …, 2023 - thelancet.com
Molnupiravir and Nirmatrelvir-ritonavir treatment within 5 days of symptom onset was
associated with a lower risk of in-hospital death compared with control subjects. The use of these …

Effectiveness of molnupiravir in high-risk patients: a propensity score matched analysis

R Najjar-Debbiny, N Gronich, G Weber… - Clinical infectious …, 2023 - academic.oup.com
… of molnupiravir treatment both for the molnupiravir group and … less likely to be treated with
molnupiravir in comparison to … disease, malignancy, and immunosuppression were each an …

Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
… /failure), severely immunocompromised persons who are not … day 29 of 1 participant treated
with molnupiravir 400 mg and 1 … of molnupiravir in the hospitalized participants studied: …

Remdesivir reduced mortality in immunocompromised patients hospitalized for COVID-19 across variant waves: findings from routine clinical practice

E Mozaffari, A Chandak, RL Gottlieb… - Clinical Infectious …, 2023 - academic.oup.com
… from AstraZeneca and participation on advisory board for … death, yet treatment strategies for
immunocompromised patients … treatment on inpatient mortality among immunocompromised

Comparative effectiveness of Paxlovid versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised patients: observational …

B Zheng, J Tazare, L Nab, A Mehrkar, B MacKenna… - medRxiv, 2023 - medrxiv.org
… clinical subgroups being underrepresented (such as immunosuppressed individuals). Several
real-… between participants treated with Paxlovid and sotrovimab or molnupiravir (Figure 1). …

[HTML][HTML] Molnupiravir versus favipiravir in at-risk outpatients with COVID-19: A randomized controlled trial in Thailand

N Salvadori, G Jourdain, R Krittayaphong… - International Journal of …, 2024 - Elsevier
… ) and immunocompromised status (yes … treatment-related AEs were rash (<1% [1/483] and
<1% [2/486]) and diarrhea (<1% [2/483] and 0% [0/486]). Four participants in the molnupiravir

Nirmatrelvir or molnupiravir use and severe outcomes from omicron infections

DY Lin, F Abi Fadel, S Huang, AT Milinovich… - JAMA Network …, 2023 - jamanetwork.com
… Design, Setting, and Participants This was a cohort study of … Patients who were
immunocompromised or who had … number of patients treated with nirmatrelvir or molnupiravir, it …

[HTML][HTML] Effectiveness of molnupiravir treatment in patients with COVID-19 in Korea: a propensity score matched study

HR Park, MG Yoo, JM Kim, SJ Bae, H Lee… - Infection & …, 2023 - ncbi.nlm.nih.gov
… for molnupiravir treatment included the following: (1) those aged ≥60 years; (2) those aged
≥18 years and are immunocompromised … , most of the participants in the PANORAMIC trial …