Neurological side effects and drug interactions of antiviral compounds against SARS‐CoV‐2

T Akhvlediani, R Bernard‐Valnet… - European Journal of …, 2023 - Wiley Online Library
treatment with molnupiravir (Table 3). A post hoc analysis examined outcomes among
immunocompromised participants… , fewer molnupiravir-treated immunocompromised patients were …

[HTML][HTML] The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

R Abdelnabi, CS Foo, SJF Kaptein, X Zhang… - …, 2021 - thelancet.com
… from nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection. …
Such drugs are also needed for the treatment of immunodeficient patients who do not mount a (…

Oral nirmatrelvir and ritonavir for coronavirus disease 2019 in vaccinated, nonhospitalized adults aged 18–50 years

JS Faust, A Kumar, J Shah, S Khadke… - Clinical Infectious …, 2023 - academic.oup.com
… from EHRs from participating healthcare organizations, … treatment with other approved
medications for COVID-19 such as monoclonal antibody, convalescent plasma, or molnupiravir for …

Availability of oral antivirals against SARS-CoV-2 infection and the requirement for an ethical prescribing approach

R Dal-Ré, SL Becker, E Bottieau… - The Lancet Infectious …, 2022 - thelancet.com
… ) of this trial, molnupiravir treatment resulted in a 3 percentage … in detail the selection criteria
of participants and how to assess … Should immunocompromised patients always have priority …

[HTML][HTML] Optimizing COVID-19 treatment in immunocompromised patients: early combination therapy with remdesivir, nirmatrelvir/ritonavir and sotrovimab

I Gentile, M Foggia, M Silvitelli, A Sardanelli… - Virology Journal, 2023 - Springer
… in an immunosuppressed patient treated with a combination of nirmatrelvir/ritonavir (N/r) plus
molnupiravir for … All procedures performed in studies involving human participants were in …

[HTML][HTML] SARS-CoV-2 rebound with and without use of COVID-19 oral antivirals

DJ Smith - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
… second-line therapy (molnupiravir) reduces the prevalence of … , such as those who are
immunocompromised (14). Two … /ritonavir treatment among immunocompromised subjects ¶¶ and …

[HTML][HTML] Oral antiviral treatments for COVID-19: opportunities and challenges

L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
… COVID-19 management, not as a competitor to vaccination. … for oral antivirals development
to treat COVID-19, highlight … (nirmatrelvir/ritonavir and molnupiravir), and present the potential …

From Clinical Trials to Communities: an observational study to evaluate the efficacy of Antiviral Therapies for Severe Acute Respiratory Syndrome Coronavirus 2 …

D Jackson, J Coulson - Medical Research Archives, 2023 - esmed.org
… The data shows that within a 28-day window from prescription, 6.2% of all the participants
in … study suggest that antiviral treatment with Paxlovid, molnupiravir and sotrovimab may be …

[HTML][HTML] First-generation oral antivirals against SARS-CoV-2

P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
participants. The number of seropositive individuals who achieved the primary endpoint was
low in the molnupiravir study (n = 5/136 in molnupiravirtreatment of immunocompromised

Effect of pre-hospitalization use of oral antiviral agents on reducing critical illness and mortality for patients with COVID-19 pneumonia

YC Yii, HM Shih, CL Chen, ZL Lai, YL Hsu… - International Journal of …, 2024 - Elsevier
… /ritonavir and molnupiravir before hospitalisation on … COVID-19, the study participants were
divided into three groups, … rates in the setting of outpatient treatment and mild disease [3,4]. …