IJ Lebish, RM Moraski - Toxicologic Pathology, 1987 - journals.sagepub.com
… overview of the mechanism of action of immunomodulatingdrug has been presented, followed by a detailed analysis of the mechanisms of action of the immunomodulator CL 246,738. …
AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… to shed light on the molecularmechanisms of the cytokines and their functions and impact on the pathology of COVID-19. Furthermore, the immunomodulatory therapeutic strategies are …
… for any understanding the role of immunomodulatorydrugs (IMIDs). These drugs are analogues of … An important part of their in vivo efficacy must be attributed to their immunomodulatory …
H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison… - Leukemia, 2010 - nature.com
… to the understanding of the role of the immunomodulatorydrug (IMiD) class. IMiDs are a group of … Molecularmechanisms whereby immunomodulatorydrugs activate natural killer cells: …
X Chang, Y Zhu, C Shi, AK Stewart - Acta Biochim Biophys Sin, 2014 - academic.oup.com
… of cell surface adhesion molecules between myeloma cells … , and the potential molecular mechanisms of IMiDs resistance … In this review, we will focus on the molecularmechanism of …
… Prior to beginning to understand the molecularmechanisms of the IMiDs, it was appreciated that this drug class displayed a wide range of biological activities, many of which appeared …
JH Kim, DH Kim, S Jo, MJ Cho, YR Cho… - … & molecular medicine, 2022 - nature.com
… the molecularmechanisms involved in regulating the activity of various types of immune cells. Identifying immune-enhancing functional foods and understanding their mechanisms of …
YX Zhu, KM Kortuem, AK Stewart - Leukemia & lymphoma, 2013 - Taylor & Francis
… Although several mechanisms have been proposed to explain the activity of thalidomide, … and immunomodulatory effects, the precise cellular targets and molecularmechanisms have …
C Riccardi, S Bruscoli, G Migliorati - Pharmacological research, 2002 - Elsevier
The development and function of cells in the immune system are regulated by many intrinsic and extrinsic factors. One class of molecule that affects immune cells belongs to the …