Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application

T Hayashi, T Hideshima, M Akiyama… - British journal of …, 2005 - Wiley Online Library
… In summary, this study defined the molecular mechanism whereby IMiDs augment NK cell
cytotoxicity observed in laboratory and clinical studies (Davies et al, 2001). Specifically, IMiDs …

Mechanisms of immunomodulation by drugs

IJ Lebish, RM Moraski - Toxicologic Pathology, 1987 - journals.sagepub.com
… overview of the mechanism of action of immunomodulating drug has been presented, followed
by a detailed analysis of the mechanisms of action of the immunomodulator CL 246,738. …

[HTML][HTML] … cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… to shed light on the molecular mechanisms of the cytokines and their functions and impact
on the pathology of COVID-19. Furthermore, the immunomodulatory therapeutic strategies are …

Immunomodulatory drugs in multiple myeloma: from molecular mechanisms of action to clinical practice

R Castelli, A Cannavò, F Conforti, G Grava… - …, 2012 - Taylor & Francis
… for any understanding the role of immunomodulatory drugs (IMIDs). These drugs are analogues
of … An important part of their in vivo efficacy must be attributed to their immunomodulatory

Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison… - Leukemia, 2010 - nature.com
… to the understanding of the role of the immunomodulatory drug (IMiD) class. IMiDs are a group
of … Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: …

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

X Chang, Y Zhu, C Shi, AK Stewart - Acta Biochim Biophys Sin, 2014 - academic.oup.com
… of cell surface adhesion molecules between myeloma cells … , and the potential molecular
mechanisms of IMiDs resistance … In this review, we will focus on the molecular mechanism of …

Immunomodulatory drugs in multiple myeloma: mechanisms of action and clinical experience

SA Holstein, PL McCarthy - Drugs, 2017 - Springer
… Prior to beginning to understand the molecular mechanisms of the IMiDs, it was appreciated
that this drug class displayed a wide range of biological activities, many of which appeared …

[HTML][HTML] Immunomodulatory functional foods and their molecular mechanisms

JH Kim, DH Kim, S Jo, MJ Cho, YR Cho… - … & molecular medicine, 2022 - nature.com
… the molecular mechanisms involved in regulating the activity of various types of immune
cells. Identifying immune-enhancing functional foods and understanding their mechanisms of …

Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

YX Zhu, KM Kortuem, AK Stewart - Leukemia & lymphoma, 2013 - Taylor & Francis
… Although several mechanisms have been proposed to explain the activity of thalidomide, …
and immunomodulatory effects, the precise cellular targets and molecular mechanisms have …

Molecular mechanisms of immunomodulatory activity of glucocorticoids

C Riccardi, S Bruscoli, G Migliorati - Pharmacological research, 2002 - Elsevier
The development and function of cells in the immune system are regulated by many intrinsic
and extrinsic factors. One class of molecule that affects immune cells belongs to the …