… Ever since discovering the fat-soluble secosteroid vitamin D, an abundance of research has
been conducted on the molecular mechanisms for the multiple health benefits of this nutrient…

… The literature provides two potential molecular mechanisms to explain leflunomide's effects
on B cells: (1) the depletion of pyrimidine pools by the inhibition of DHODH, and (2) the …

… known immunomodulatory drug classes and revealed several clinically approved drugs that
… Thus, the recapitulation of the effects of biologicals with well-defined mechanisms of action, …

… Immunomodulatory drugs (IMiDs) are a class of molecules … They have immunomodulatory,
antiangiogenic and proapoptotic … Here we report the mechanisms of action of IMiDs in acute …

… These responses involve many cell types that express recognition molecules such as Toll-like …
and immunomodulatory drugs can be characterized by their associated mechanism of …

… Analysis of recent data suggests that these drugs increase the incidence of venous
thromboembolism (VTE).57, 58 The exact mechanism that underlies this effect of ESAs is not clear, …

… To study the molecular mechanism of action of this class of drugs, we have focused on the
proximal and immediate molecular events that follow exposure of cells to IMiDs drugs in the …

… immunomodulatory plants are currently identified to find novel immunomodulatory drugs.
Of … assay is of cellular and humoral immune molecular mechanisms. Therefore, the review’s …

… Leflunomide (HWA 486 or SU101), a novel immunomodulatory drug, is currently being
evaluated in phase I clinical trials for the control of kidney transplant rejection and phase II clinical …

… immunomodulatory potential of cucurbitacins, identifying the most studied compounds in this
area and exploring their mechanisms … The most cited mechanisms were inhibition of COX-2 …