Immunomodulatory drugs in multiple myeloma: from molecular mechanisms of action to clinical practice

R Castelli, A Cannavò, F Conforti, G Grava… - …, 2012 - Taylor & Francis
… for any understanding the role of immunomodulatory drugs (IMIDs). These drugs are analogues
of … An important part of their in vivo efficacy must be attributed to their immunomodulatory

Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison… - Leukemia, 2010 - nature.com
… of the role of the immunomodulatory drug (IMiD) class. IMiDs are … targets and the exact
mechanism of actions of IMiDs in MM … Molecular mechanisms whereby immunomodulatory drugs

Mechanisms of immunomodulation by drugs

IJ Lebish, RM Moraski - Toxicologic Pathology, 1987 - journals.sagepub.com
… overview of the mechanism of action of immunomodulating drug has been presented, followed
by a detailed analysis of the mechanisms of action of the immunomodulator CL 246,738. …

Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features

F Rommasi, MJ Nasiri, M Mirsaeidi - Molecular and cellular biochemistry, 2022 - Springer
… In this regard, the application of immunomodulatory drugs has … mechanism of action for
several pivotal immunomodulatory and immunosuppressant agents pertaining to different drug

Immunomodulatory drugs in multiple myeloma: mechanisms of action and clinical experience

SA Holstein, PL McCarthy - Drugs, 2017 - Springer
… insight into their mechanism of action. Here, the clinical efficacy of these agents in myeloma
is reviewed and the structure-function relationship, the molecular mechanisms of action, and …

Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

YX Zhu, KM Kortuem, AK Stewart - Leukemia & lymphoma, 2013 - Taylor & Francis
… Although several mechanisms have been proposed to explain the activity of thalidomide, …
and immunomodulatory effects, the precise cellular targets and molecular mechanisms have …

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

X Chang, Y Zhu, C Shi, AK Stewart - Acta Biochim Biophys Sin, 2014 - academic.oup.com
… of cell surface adhesion molecules between myeloma cells … , and the potential molecular
mechanisms of IMiDs resistance … will focus on the molecular mechanism of IMiDs' action in the …

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… to shed light on the molecular mechanisms of the cytokines and their functions and impact
on the pathology of COVID-19. Furthermore, the immunomodulatory therapeutic strategies are …

Mechanisms of action and clinical application of macrolides as immunomodulatory medications

S Kanoh, BK Rubin - Clinical microbiology reviews, 2010 - Am Soc Microbiol
… Although molecular mechanisms of macrolide action on Ca 2+ dynamics remain unclear,
erythromycin does not affect verapamil-sensitive, voltage-dependent Ca 2+ channels (151, 346…

Immunomodulatory functional foods and their molecular mechanisms

JH Kim, DH Kim, S Jo, MJ Cho, YR Cho… - … & Molecular Medicine, 2022 - nature.com
molecular mechanisms involved in regulating the activity of various types of immune cells.
Identifying immune-enhancing functional foods and understanding their mechanisms of action