Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, AK Stewart, P Neeson, S Harrison… - Leukemia, 2010 - nature.com
… In multiple myeloma (MM), the interplay between malignant plasma cells and their micro-…
to the understanding of the role of the immunomodulatory drug (IMiD) class. IMiDs are a group …

Immunomodulatory drugs (IMiDs) in multiple myeloma

S Raza, RA Safyan, S Lentzsch - Current cancer drug targets, 2017 - ingentaconnect.com
Background: Multiple myeloma (MM) is a hematological … with the incorporation of
immunomodulatory drugs (IMiDs) and … -diagnosed multiple myeloma, relapsed refractory myeloma

Immunomodulatory drugs in the treatment of multiple myeloma

Y Abe, T Ishida - Japanese Journal of Clinical Oncology, 2019 - academic.oup.com
multiple myeloma was quite poor in the last century, but it has significantly improved with the
incorporation of novel agents, immunomodulatory drugs (… and immunomodulatory activities, …

Immunomodulatory drugs in multiple myeloma: mechanisms of action and clinical experience

SA Holstein, PL McCarthy - Drugs, 2017 - Springer
… Over the last two decades, the outcomes for patients with multiple myeloma, a plasma cell
malignancy, have dramatically improved. The development of the immunomodulatory drugs (…

[HTML][HTML] Developing next generation immunomodulatory drugs and their combinations in multiple myeloma

A Thakurta, WE Pierceall, MD Amatangelo, E Flynt… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Multiple Myeloma (MM) is an incurable malignancy with current treatment choices primarily
comprising combination regimens implemented with a risk-adapted approach. Cereblon (…

Immunomodulatory drugs in multiple myeloma

S Andhavarapu, V Roy - Expert review of hematology, 2013 - Taylor & Francis
… The introduction of new agents immunomodulatory drugs (IMiDs) and … multiple myeloma
(MM). Thalidomide was the first immunomodulatory agent approved for use in myeloma. …

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

X Chang, Y Zhu, C Shi, AK Stewart - Acta Biochim Biophys Sin, 2014 - academic.oup.com
Although immunomodulatory drugs (IMiDs), such as thalidomide, lenalidomide, and
pomalidomide, are widely used in the treatment of multiple myeloma (MM), the molecular …

Mechanism of immunomodulatory drugs in multiple myeloma

L Sedlarikova, L Kubiczkova, S Sevcikova, R Hajek - Leukemia research, 2012 - Elsevier
… of immunomodulatory drugs into the treatment protocol, the outcome of multiple myeloma
% of patients surviving for 10 years thus shifting multiple myeloma to a treatable condition. …

Maintenance therapy with immunomodulatory drugs in multiple myeloma: a meta-analysis and systematic review

Y Wang, F Yang, Y Shen, W Zhang… - Journal of the …, 2016 - academic.oup.com
Immunomodulatory drugs (IMiDs) and proteasome inhibitors have dramatically changed
management of multiple myeloma (MM). While MM remains incurable, consolidation and …

The role of immunomodulatory drugs in multiple myeloma

KC Anderson - Seminars in hematology, 2003 - Elsevier
Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in
patients with relapsed multiple myeloma. Blood 2002;100:3063–3067.17 Copyright American …