… Severe and critical COVID-19 cases demand oxygen therapy and mechanical ventilator
support. Various drugs, including immunomodulatory and immunosuppressive agents (eg, …

… therapies [6]. This systematic review summarizes the current therapeutic approaches for
COVID-19 … , currently under investigation in clinical trials for COVID-19. The hypothesized anti-…

… the belief that immunomodulatory therapies have been hailed … servers, every new proposed
therapy has garnered extensive … one of the first tested immunomodulatory agents, although …

… of gamma globulin) therapy for severe COVID-19 patients. We discuss both their therapeutic
effects and side effects that should be taken into consideration for their clinical application. …

… immunomodulatory therapies have indeed proven beneficial in patients with SARS, MERS,
and COVID-19… , was effective as a supportive therapy in selected COVID-19 patients. SARS-…

… 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) …
the different immunomodulatory strategies tested in critically ill patients with COVID-19. …

… displaying considerable immunomodulation activity … immunomodulation products as potential
therapy for the management of infectious diseases, including viral ones such as COVID-19. …

… the study utilized an open-label or placebo-controlled design, accounted for the inconsistent
mortality effects reported in clinical trials of immunomodulator therapies for COVID-19. …

… However, the ICMR advises HCQ use for prophylaxis of COVID-19 in high-risk individuals
such as HCWs. Immunomodulatory therapies such as tocilizumab may be tried in moderate to …

… immunomodulation therapy with an SCD demonstrated safety without any device-related
serious adverse events. As a rescue therapy in COVID-19 ICU … hyperinflammation of COVID-19. …