Of bats and men: Immunomodulatory treatment options for COVID-19 guided by the immunopathology of SARS-CoV-2 infection

MJ Christie, AT Irving, SC Forster, BJ Marsland… - Science …, 2021 - science.org
… life-saving immunomodulatory therapies. The need for such therapies in COVID-19 is unlikely
… Here, we summarize current knowledge on COVID-19 immunopathogenesis in relation to …

… of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… in severely ill patients with COVID-19. This cascade of events … inflammatory markers in
COVID-19-related complications. … drugs, therapies, and control measures to counter COVID-19. …

Immune immunomodulation in coronavirus disease 2019 (COVID-19): strategic considerations for personalized therapeutic intervention

MW Hall, I Joshi, L Leal, EE Ooi - Clinical Infectious Diseases, 2022 - academic.oup.com
Immunomodulatory therapies that are, in our view, likely to be successful in patients with
COVID-19 are those that are tailored to the patient’s immunophenotype in real time. Further …

Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19

D Brain, A Plant-Hately, B Heaton, U Arshad… - Advanced Drug Delivery …, 2021 - Elsevier
… pathology behind COVID-19 is complex … COVID-19, and their contribution to pathogen
clearance and damage to then discuss possible therapeutic options involving immunomodulatory

[HTML][HTML] In-vitro evaluation of the immunomodulatory effects of Baricitinib: Implication for COVID-19 therapy

L Petrone, E Petruccioli, T Alonzi, V Vanini, G Cuzzi… - Journal of Infection, 2021 - Elsevier
Objective Baricitinib seems a promising therapy for COVID-19. To fully-investigate its effects,
we in-vitro evaluated the impact of baricitinib on the SARS-CoV-2-specific-response using …

Hyperinflammation and the utility of immunomodulatory medications in children with COVID-19

T Tanner, DM Wahezi - Paediatric Respiratory Reviews, 2020 - Elsevier
COVID-19 disease. There is accumulating evidence that morbidity and mortality in COVID-19
into immunomodulatory therapies aimed at targeting the excessive host immune response. …

Immunotherapeutic approaches to curtail COVID-19

H Owji, M Negahdaripour, N Hajighahramani - International …, 2020 - Elsevier
… Although the role of the immune system in overcoming COVID-19 is … COVID-19 is
presented with a focus on convalescent plasma therapy, antibodies, and immunomodulators

[HTML][HTML] Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish …

G Abelenda-Alonso, A Rombauts, C Gudiol… - Clinical Microbiology …, 2021 - Elsevier
… such as the use of immunomodulatory drugs. Therefore, we aim to address risk factors and
… of COVID-19 patients with hospital-acquired BSI, focusing on the use of immunomodulatory

Immunomodulatory therapies for SARS-CoV-2 infection: a systematic literature review to inform EULAR points to consider

A Alunno, A Najm, X Mariette, G De Marco… - Annals of the …, 2021 - ard.bmj.com
… evidence about immunomodulatory therapies for the management of COVID-19, conclusive
… EULAR initiative to formulate PtC on COVID-19 pathophysiology and immunomodulatory

Immunotherapies and immunomodulatory approaches in clinical trials-a mini review

M Iqbal Yatoo, Z Hamid, I Rather… - Human vaccines & …, 2021 - Taylor & Francis
… Citation85 have projected to use SARS-CoV-2-specific and HLA-matched cytotoxic T cells
arranged from convalescent COVID-19 patients as need of the hour therapy in COVID 19