[HTML][HTML] The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
therapies targeting immunosuppression have been suggested to help combat the cytokine
storm… (MSCs), owing to their powerful immunomodulatory ability, have shown promise in early …

[HTML][HTML] Cytokine storm in novel coronavirus disease (COVID-19): expert management considerations

Y Mehta, SB Dixit, KG Zirpe… - Indian journal of critical …, 2020 - ncbi.nlm.nih.gov
… In our opinion, it is advisable to initiate these immunomodulatory therapies early in the
course of the disease, ie, at the stage of pneumonia to prevent possible cytokine storm and …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… Besides anti-viral agents, treatment of immunologic complications including cytokine storm
using appropriate immunosuppressive and immunomodulatory drugs is essential [40, 41]. …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… lungs, leading to a cytokine storm and eventually damaging the … immunomodulatory and
immunosuppressive therapies … It is necessary to confirm the therapeutic effects, investigate the …

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
therapeutic drugs or vaccines are available to treat COVID-19. In this review, we intended to
describe how cytokine storm is … response due to cytokine storm during COVID-19 infection …

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
… cannot be downplayed, the use of immunomodulatory therapy is potentially effective,
considering that SARS-CoV-2 drives immune dysfunction and induces hyperinflammation and a …

COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
Immunomodulatory therapies aimed at alleviating the cytokine storm originated by COVID-19
should be carefully designed in order to avoid putting these patients at a higher risk of …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… IVIG can elicit passive immunity, anti-inflammatory, and immunomodulatory effects that can
… (FcγRs), to exert the functions of immunomodulation (81). Ma and colleagues detailed a …

[HTML][HTML] … of cytokines storm on prognosis of SARS-CoV-2 infection through immune response: dynamic analysis and optimal control with immunomodulatory therapy

P Rana, S Chauhan, A Mubayi - The European Physical Journal Special …, 2022 - Springer
… followed by the curve-fit for the cytokines using real data and an optimization algorithm …
immunomodulatory therapy (tocilizumab) can act as a key component to control cytokines storm

[HTML][HTML] Fostering mesenchymal stem cell therapy to halt cytokine storm in COVID-19

M Jeyaraman, A John, S Koshy, R Ranjan… - … et Biophysica Acta (BBA …, 2021 - Elsevier
immunomodulatory factors or through direct cell-cell contact. Due to their … cytokines (IFN-α,
TNF-γ, IL-1β, IL-6, IL-12, IL-8, IL-33, and TGF-β) [53]. The mechanism of the cytokine storm