A 21st century evil: immunopathology and new therapies of COVID-19

TF Silva, F Tomiotto-Pellissier, RA Sanfelice… - Frontiers in …, 2020 - frontiersin.org
… in the lungs, and cytokine storms, which may contribute to its … with the disease’s
immunopathogenesis. Among them, IL-1β … , its exact role in the immunopathogenesis of the …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

Cytokine storm: When the immune system goes into overdrive

PP Kale, A Mani, S Gurha, HN Abhishek… - Journal of Cellular …, 2023 - content.iospress.com
… Supportive care: Patients with cytokine storm may require oxygen therapy, mechanical
ventilation, and other supportive care measures to maintain organ function and manage …

[HTML][HTML] Immunopathogenesis of COVID-19: summary and possible interventions

FH Jacques, E Apedaile - Frontiers in immunology, 2020 - frontiersin.org
… Anti PD1 therapy in animal models of HIV and TB showed a reduced hyper activation of … of
cytokine storms and immune dysregulation (24). Early intervention with an anti PD-L1 therapy

Immunotherapy summary for cytokine storm in COVID-19

Y Li, W Zhao, J Liu, Z Chen, Q Lv… - Frontiers in Pharmacology, 2021 - frontiersin.org
… These cytokine inhibitors have therapeutic benefits for patients with COVID-19 but there are
… the level of cytokine storms in the circulatory system. Second, the levels of cytokines in the …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… Furthermore, cytokine storm can cause post-COVID-19 … in COVID-19-related cytokine storm
and its association with multi-… potential therapeutic targets to control cytokine storm wishing …

… pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine storm and inflammatory responses

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
therapeutic strategies focusing on immunomodulation have been tested out to assuage the
cytokine storm … of hyperinflammatory response or cytokine storm with organ damage and the …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
Cytokine storm has been … immunopathogenesis of COVID-19. Furthermore, we review the
possible role of an anti-IL-1 medication such as Anakinra in the suppression of cytokine storm

Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy

S Fiorino, C Gallo, M Zippi, S Sabbatani… - Aging clinical and …, 2020 - Springer
… Our current knowledge concerning the immunopathogenesis of SARS-CoV- and SARS-CoV-2-mediated
disease suggests that both the type and the quality of the immune response …

[PDF][PDF] Immunopathogenesis of COVID-19: Looking into the Eye of the Cytokine Storm

D Hamal, N Nayak, R Shrestha… - Nepal Journal Of …, 2022 - njmsmanipal.com.np
… proinflammatory events is known as a cytokine storm. … -beta and IL-6 throughout their clinical
course as compared to those who survived.Overall, it is undoubtedly true that cytokine storm