Immunopathogenesis of coronavirus-induced acute respiratory distress syndrome (ARDS): potential infection-associated hemophagocytic lymphohistiocytosis

C Quan, C Li, H Ma, Y Li, H Zhang - Clinical Microbiology Reviews, 2020 - Am Soc Microbiol
… Activated macrophages mainly contribute to the cytokine storm and hemophagocytosis, … of
biologic therapy, but when and how to use cytokine-directed therapeutics remain challenging. …

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
… of advanced COVID-19 is cytokine release syndrome or “cytokine storm” that is attributable
to … Furthermore, the potential Treg-boosting effect of therapeutic agents used in the treatment …

COVID-19: more than a cytokine storm

G Riva, V Nasillo, E Tagliafico, T Trenti, P Comoli… - Critical care, 2020 - Springer
… syndrome and related immunopathogenesis have been … cell immunity, while suppressing
the emergent cytokine storm [7,8,9]. … antigen receptor (CAR) T cell therapy, as well as in Kaposi …

[HTML][HTML] Cytokine storm syndrome in severe COVID-19

P Ruscitti, O Berardicurti, A Iagnocco… - Autoimmunity …, 2020 - ncbi.nlm.nih.gov
… The term cytokine storm syndrome accommodates the … Considering iatrogenic trigger, a
cytokine storm syndrome … of these therapies, as shown by T cell-engaging therapies and CD19-…

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
… adjuvants to ameliorate the cytokine storm; in combination with … the immunopathogenesis of
the cytokine storm observed in … -19 when used in conjunction with standard antiviral therapy. …

Potential therapeutic applications of extracellular vesicles in the immunopathogenesis of COVID-19

M Motallebnezhad, M Omraninava, HEG Ghaleh… - … -Research and Practice, 2023 - Elsevier
therapeutic strategy that could ameliorate the cytokine storm … antiviral drugs may have
therapeutic benefits in patients with … potential of EVs as a therapeutic candidate in the diagnosis …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… Available evidence indicate that the so called “cytokine storm… -receptor system in the cytokine
storm related to SARS-CoV-2 … the use of Tocilizumab as a therapeutic agent was proposed. …

Immunopathogenesis and perspectives for immunotherapy of coronavirus infection

A Simbirtsev - 2021 - covid19.neicon.ru
therapy at the stage of severe pneumonia and cytokine storm development, passive
immunization with blood plasma of recovered patients or therapeutic monoclonal antibodies, pro- …

Cytokines in the immunity and immunopathogenesis in leishmaniases

B Saha, R Silvestre - Cytokine, 2021 - Elsevier
… viral infections supra-physiologic levels of cytokine storms are produced culminating in multi-…
The current anti-leishmanial arsenal has also a narrow therapeutic index, ie, the therapeutic

Comparative study of cytokine storm treatment in patients with COVID-19 pneumonia using immunomodulators

F Marc, CM Moldovan, A Hoza, S Magheru… - Journal of Clinical …, 2022 - mdpi.com
… The therapeutic options for cytokine storms are still controversial, requiring further … internal
medicine department who developed a cytokine storm (diagnosed by clinical and biochemical …